Rabbit anti-Human ZFYVE1 Polyclonal Antibody | anti-ZFYVE1 antibody

ZFYVE1, NT (ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1, Zinc finger FYVE domain-containing protein 1, Double FYVE-containing protein 1, SR3, Tandem FYVE fingers-1) (FITC)

Cat. Num. AAA6365252

• Gene Names: ZFYVE1; SR3; DFCP1; TAFF1; ZNFN2A1; PPP1R172
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: ZFYVE1; Polyclonal Antibody; NT (ZFYVE1; DFCP1; KIAA1589; TAFF1; ZNFN2A1; Zinc finger FYVE domain-containing protein 1; Double FYVE-containing protein 1; SR3; Tandem FYVE fingers-1) (FITC); Tandem FYVE fingers-1; anti-ZFYVE1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
• Sequence Length: 362

• Applicable Applications for anti-ZFYVE1 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: ZFYVE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-173 amino acids from the N-terminal region of human ZFYVE1.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(ZFYVE1 Antibody (N-term) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the ZFYVE1 antibody detected the ZFYVE1 protein (arrow).)

Related Product Information for anti-ZFYVE1 antibody

The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate (PtdIns(3)P)-containing membranes. This gene encodes a protein which contains two zinc-binding FYVE domains in tandem. This protein displays a predominantly Golgi, endoplasmic reticulum and vesicular distribution. Alternatively spliced transcript variants have been found for this gene, and they encode two isoforms with different sizes.

Product Categories/Family for anti-ZFYVE1 antibody

Antibodies; Transcription Factors; Zinc (Ring) Finger

References

Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004). Heilig, R., et al. Nature 421(6923):601-607(2003). Krugmann, S., et al. Mol. Cell 9(1):95-108(2002). Ridley, S.H., et al. J. Cell. Sci. 114 (PT 22), 3991-4000 (2001): Cheung, P.C., et al. Biochem. J. 355 (PT 1), 113-121 (2001).

NCBI and Uniprot Product Information

• NCBI GI #: 30795182
• NCBI GeneID: 53349
• NCBI Accession #: NP_848535.1; NP_067083.1
• NCBI GenBank Nucleotide #: NP_848535.1
• UniProt Accession #: Q9HBF4
• NCBI Official Full Name: zinc finger FYVE domain-containing protein 1 isoform 2
• NCBI Official Synonym Full Names: zinc finger FYVE-type containing 1
• NCBI Official Symbol: ZFYVE1
• NCBI Official Synonym Symbols: SR3; DFCP1; TAFF1; ZNFN2A1; PPP1R172
• NCBI Protein Information: zinc finger FYVE domain-containing protein 1
• UniProt Protein Name: Zinc finger FYVE domain-containing protein 1
• Protein Family: Zinc finger FYVE domain-containing protein
• UniProt Gene Name: ZFYVE1
• UniProt Synonym Gene Names: DFCP1; KIAA1589; TAFF1; ZNFN2A1
• UniProt Entry Name: ZFYV1_HUMAN

NCBI Description

The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate-containing membranes. This protein contains two zinc-binding FYVE domains in tandem and is reported to localize to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]