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Western Blot (WB) (Western Blot analysis of A549, K562 and PC3 cell using ZFP42 Polyclonal Antibody at dilution of 1:500)

Rabbit ZFP42 Polyclonal Antibody | anti-ZFP42 antibody

ZFP42 Polyclonal Antibody

Gene Names
ZFP42; REX1; REX-1; ZNF754; zfp-42
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Antigen affinity purification
Synonyms
ZFP42; Polyclonal Antibody; ZFP42 Polyclonal Antibody; REX1; ZNF754; anti-ZFP42 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1.8mg/mL (varies by lot)
Sequence Length
310
Applicable Applications for anti-ZFP42 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Synthetic peptide of human ZFP42
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Western Blot (WB)

(Western Blot analysis of A549, K562 and PC3 cell using ZFP42 Polyclonal Antibody at dilution of 1:500)

Western Blot (WB) (Western Blot analysis of A549, K562 and PC3 cell using ZFP42 Polyclonal Antibody at dilution of 1:500)
Related Product Information for anti-ZFP42 antibody
Rex-1 (for reduced expression), also designated zinc finger protein 42 (ZFP42), is an acidic zinc finger protein. Rex-1 contains four repeats of the zinc finger nucleic acid-binding motif and a potential acidic activator domain, suggesting that it is a regulatory protein. Rex-1 localizes to the nucleus and is highly expressed in embryonic stem (ES) and undifferentiated murine F9 teratocarcinoma cells. At the transcriptional level, expression of Rex-1 is reduced when F9 cells are induced to differentiate by the addition of retinoic acid (RA), and Rex-1 repression is enhanced by E1A. The Oct-3/4 transcription factor can either activate or repress the Rex-1 promoter, depending on the cellular environment, while Oct-6 can lower the expression of Rex-1.
Product Categories/Family for anti-ZFP42 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
34,802 Da
NCBI Official Full Name
zinc finger protein 42 homolog
NCBI Official Synonym Full Names
ZFP42 zinc finger protein
NCBI Official Symbol
ZFP42
NCBI Official Synonym Symbols
REX1; REX-1; ZNF754; zfp-42
NCBI Protein Information
zinc finger protein 42 homolog; REX1 transcription factor; reduced expression protein 1; zinc finger protein 754
UniProt Protein Name
Zinc finger protein 42 homolog
Protein Family
UniProt Gene Name
ZFP42
UniProt Synonym Gene Names
REX1; ZNF754; Zfp-42; REX-1; hREX-1
UniProt Entry Name
ZFP42_HUMAN

Uniprot Description

ZFP42: Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Required for efficient elongation of TSIX, a non-coding RNA antisense to XIST. Binds DXPas34 enhancer within the TSIX promoter. Involved in ES cell self-renewal. Belongs to the krueppel C2H2-type zinc-finger protein family.

Protein type: C2H2-type zinc finger protein; DNA-binding

Chromosomal Location of Human Ortholog: 4q35.2

Cellular Component: protein complex; cytoplasm; nucleus

Molecular Function: sequence-specific DNA binding; metal ion binding; transcription factor activity

Biological Process: meiosis; transcription, DNA-dependent; regulation of transcription, DNA-dependent; in utero embryonic development; male gonad development; spermatid development; female gonad development

Research Articles on ZFP42

Similar Products

Product Notes

The ZFP42 zfp42 (Catalog #AAA2516848) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZFP42 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ZFP42 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the ZFP42 zfp42 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZFP42, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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