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Western Blot (WB) (Western blot analysis of Zeta crystallin expression in K562 (A), mouse liver (B), mouse brain (C), rat kidney (D) whole cell lysates.)

Rabbit Zeta crystallin Polyclonal Antibody | anti-CRYZ antibody

Anti-Zeta crystallin Antibody

Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Purified by Immunogen Affinity Chromatography
Synonyms
Zeta crystallin; Polyclonal Antibody; Anti-Zeta crystallin Antibody; Quinone oxidoreductase; NADPH:quinone reductase; Zeta-crystallin; anti-CRYZ antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of Zeta crystallin protein.
Purity/Purification
Purified by Immunogen Affinity Chromatography
Form/Format
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
Applicable Applications for anti-CRYZ antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant fusion protein of human Zeta crystallin. The exact sequence is proprietary.
Preparation and Storage
Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of Zeta crystallin expression in K562 (A), mouse liver (B), mouse brain (C), rat kidney (D) whole cell lysates.)

Western Blot (WB) (Western blot analysis of Zeta crystallin expression in K562 (A), mouse liver (B), mouse brain (C), rat kidney (D) whole cell lysates.)
Related Product Information for anti-CRYZ antibody
Rabbit polyclonal antibody to Zeta crystallin

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
37.6 kDa (352aa) confirmed by MALDI-TOF
NCBI Official Full Name
quinone oxidoreductase isoform a
NCBI Official Synonym Full Names
crystallin zeta
NCBI Official Symbol
CRYZ
NCBI Protein Information
quinone oxidoreductase
UniProt Protein Name
Quinone oxidoreductase
Protein Family
UniProt Gene Name
CRYZ

NCBI Description

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist. [provided by RefSeq, Sep 2008]

Uniprot Description

Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding.

Research Articles on CRYZ

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Product Notes

The CRYZ cryz (Catalog #AAA8306378) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Zeta crystallin Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Zeta crystallin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the CRYZ cryz for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Zeta crystallin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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