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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human testis tissue using MBS7046616 at dilution 1:100)

Rabbit anti-Human ZDHHC17 Polyclonal Antibody | anti-ZDHHC17 antibody

ZDHHC17 Antibody

Gene Names
ZDHHC17; HIP3; HYPH; HIP14; HSPC294
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
ZDHHC17; Polyclonal Antibody; ZDHHC17 Antibody; Palmitoyltransferase ZDHHC17Curated; Huntingtin yeast partner H; anti-ZDHHC17 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
632
Applicable Applications for anti-ZDHHC17 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: IHC: 1:20-1:200
Species
Human
Immunogen
Recombinant human Palmitoyltransferase ZDHHC17 protein (170-310AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human testis tissue using MBS7046616 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human testis tissue using MBS7046616 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human placenta tissues using MBS7046616 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human placenta tissues using MBS7046616 at dilution 1:100)
Related Product Information for anti-ZDHHC17 antibody
Palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, DLG4/PSD95, GAD2, SYT1 and HD (PubMed:15603740, PubMed:15489887, PubMed:19139280). Palmitoylates MPP1 in erythrocytes (PubMed:22496366). May be involved in the sorting or targeting of critical proteins involved in the initiating events of endocytosis at the plasma membrane (PubMed:12393793). May play a role in Mg(2+) transport (PubMed:18794299).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,845 Da
NCBI Official Full Name
palmitoyltransferase ZDHHC17
NCBI Official Synonym Full Names
zinc finger DHHC-type containing 17
NCBI Official Symbol
ZDHHC17
NCBI Official Synonym Symbols
HIP3; HYPH; HIP14; HSPC294
NCBI Protein Information
palmitoyltransferase ZDHHC17
UniProt Protein Name
Palmitoyltransferase ZDHHC17
Protein Family
UniProt Gene Name
ZDHHC17
UniProt Synonym Gene Names
DHHC-17
UniProt Entry Name
ZDH17_HUMAN

Uniprot Description

HIP14: a palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, PSD-95, GAD2, SYT1 and Huntingtin. May be involved in the sorting or targeting of critical proteins involved in the initiating events of endocytosis at the plasma membrane. May be involved in the NF-kappa-B signaling pathway. Can cause cellular transformation, and is up-regulated in a number of types of human tumors. Expressed in all brain regions. Expression is highest in the cortex, cerebellum, occipital lobe and caudate, and lowest in the spinal cord. Expression is also seen in testis, pancreas, heart and kidney. Three alternatively spliced isoforms have been described.

Protein type: Membrane protein, multi-pass; Transferase; Membrane protein, integral; Tumor suppressor; EC 2.3.1.225

Chromosomal Location of Human Ortholog: 12q21.2

Cellular Component: cytoplasm; Golgi apparatus; Golgi membrane; intracellular membrane-bound organelle

Molecular Function: identical protein binding; magnesium ion transmembrane transporter activity; palmitoyltransferase activity; protein binding; protein-cysteine S-palmitoleyltransferase activity; signal transducer activity

Biological Process: lipoprotein transport; positive regulation of I-kappaB kinase/NF-kappaB cascade; protein palmitoylation

Research Articles on ZDHHC17

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Product Notes

The ZDHHC17 zdhhc17 (Catalog #AAA7046616) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZDHHC17 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZDHHC17 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Recommended dilution: IHC: 1:20-1:200. Researchers should empirically determine the suitability of the ZDHHC17 zdhhc17 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZDHHC17, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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