Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using ZCCHC8 antibody.)
Rabbit anti-Human, Mouse ZCCHC8 Polyclonal Antibody | anti-ZCCHC8 antibody
ZCCHC8 Polyclonal Antibody
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Affinity purification
Synonyms
ZCCHC8; Polyclonal Antibody; ZCCHC8 Polyclonal Antibody; zinc finger CCHC-type containing 8; anti-ZCCHC8 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 50% glycerol, pH7.4
Applicable Applications for anti-ZCCHC8 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant fusion protein of human ZCCHC8 (NP_060082.2).
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using ZCCHC8 antibody.)
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using ZCCHC8 antibody.)
Related Product Information for anti-ZCCHC8 antibody
This gene encodes a scaffold protein which serves as an assessory factor to the nuclear RNA exosome complex. The encoded protein forms a trimeric human nuclear exosome targeting (NEXT) complex, together with hMTR4 and the RNA-binding factor RBM7 which promotes the exosomal degradation of non-coding promoter-upstream transcripts, enhancer RNAs and 3'-extended products of histone- and small nuclear RNA transcription. This complex is also thought to recruit the exosome to degrade intronic RNAs via its interaction with both the exosome and the spliceosome. It contains both an N-terminal zinc-knuckle domain and a C-terminal proline-rich domain.
Product Categories/Family for anti-ZCCHC8 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
78,577 Da
NCBI Official Full Name
zinc finger CCHC domain-containing protein 8
NCBI Official Synonym Full Names
zinc finger, CCHC domain containing 8
NCBI Official Symbol
ZCCHC8
NCBI Protein Information
zinc finger CCHC domain-containing protein 8
UniProt Protein Name
Zinc finger CCHC domain-containing protein 8
Protein Family
UniProt Gene Name
ZCCHC8
UniProt Entry Name
ZCHC8_HUMAN
Uniprot Description
ZCCHC8: May be involved in pre-mRNA splicing. Belongs to the ZCCHC8 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Spliceosome
Chromosomal Location of Human Ortholog: 12q24.31
Cellular Component: nucleoplasm; nucleus
Molecular Function: protein binding; zinc ion binding
Biological Process: nuclear mRNA splicing, via spliceosome
Research Articles on ZCCHC8
Similar Products
Product Notes
The ZCCHC8 zcchc8 (Catalog #AAA9434554) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZCCHC8 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ZCCHC8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the ZCCHC8 zcchc8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZCCHC8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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