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Western Blot (WB) (Western blot analysis of ZBTB8 in mouse spleen tissue lysate with ZBTB8 antibody at 1 ug/mL.)

Rabbit anti-Human, Mouse ZBTB8 Polyclonal Antibody | anti-ZBTB8 antibody

ZBTB8 Antibody

Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity chromatography purified via peptide column
Synonyms
ZBTB8; Polyclonal Antibody; ZBTB8 Antibody; Zinc finger and BTB domain-containing protein 8; ZBTB8A; BOZ-F1; anti-ZBTB8 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
At least two isoforms of ZBTB8 are known to exist; this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other ZBTB protein family members.
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
338
Applicable Applications for anti-ZBTB8 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen Type
Peptide
Immunogen Description
Raised against a 17 amino acid peptide near the carboxy terminus of human ZBTB8.
Target Name
ZBTB8
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of ZBTB8 in mouse spleen tissue lysate with ZBTB8 antibody at 1 ug/mL.)

Western Blot (WB) (Western blot analysis of ZBTB8 in mouse spleen tissue lysate with ZBTB8 antibody at 1 ug/mL.)

Immunohistochemistry (IHC)

(Immunohistochemistry of ZBTB8 in human spleen tissue with ZBTB9 antibody at 2.5 ug/mL.)

Immunohistochemistry (IHC) (Immunohistochemistry of ZBTB8 in human spleen tissue with ZBTB9 antibody at 2.5 ug/mL.)
Related Product Information for anti-ZBTB8 antibody
The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB8, also known as BOZ-F1, is present in multiple tissues, and is highly expressed in the cytoplasm of the placenta. While little is known about ZBTB8, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Another ZBTB proteins, ZBTB7A, has been implicated as a proto-oncogene whose overexpression contributes to malignancy in breast cancer, suggesting that ZBTB8 may act as a transcriptional repressor or be involved in tumorigenesis.
Product Categories/Family for anti-ZBTB8 antibody

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
38,344 Da
UniProt Protein Name
Zinc finger and BTB domain-containing protein 8A
UniProt Gene Name
ZBTB8A
UniProt Synonym Gene Names
BOZF1; BOZ-F1
UniProt Entry Name
ZBT8A_HUMAN

Uniprot Description

ZBTB8: May be involved in transcriptional regulation. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 1p35.1

Cellular Component: nucleus

Molecular Function: DNA binding; metal ion binding

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent

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Product Notes

The ZBTB8 zbtb8a (Catalog #AAA9405527) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZBTB8 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ZBTB8 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the ZBTB8 zbtb8a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZBTB8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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