Goat ZBTB24 Polyclonal Antibody | anti-ZBTB24 antibody
Goat anti-ZBTB24 (aa232-245) Antibody
Western Blot: Approx 80kDa band observed in lysates of cell line Daudi (calculated MW of 78.3kDa according to NP_055612.2). Recommended concentration: 1-3ug/ml.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein similar to a protein in rodents which is induced by bone morphogenic protein 2 in vitro. [provided by RefSeq, Aug 2011]
Uniprot Description
ZBTB24: May be involved in BMP2-induced transcription. Defects in ZBTB24 are the cause of immunodeficiency- centromeric instability-facial anomalies syndrome type 2 (ICF2). A rare disorder characterized by a variable immunodeficiency resulting in recurrent infections, facial anomalies, and branching of chromosomes 1, 9, and 16. Other variable symptoms include growth retardation, failure to thrive, and psychomotor retardation. Laboratory studies show limited hypomethylation of DNA in a small fraction of the genome in some, but not all, patients. Belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 6q21
Cellular Component: nucleus
Molecular Function: DNA binding; metal ion binding; protein binding
Biological Process: hemopoietic progenitor cell differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent
Disease: Immunodeficiency-centromeric Instability-facial Anomalies Syndrome 2
Research Articles on ZBTB24
Similar Products
Product Notes
The ZBTB24 zbtb24 (Catalog #AAA423011) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-ZBTB24 (aa232-245) Antibody reacts with Tested: Human; Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZBTB24 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 8000. Western Blot: Approx 80kDa band observed in lysates of cell line Daudi (calculated MW of 78.3kDa according to NP_055612.2). Recommended concentration: 1-3ug/ml. Researchers should empirically determine the suitability of the ZBTB24 zbtb24 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: PVEKDENYDP KTED. It is sometimes possible for the material contained within the vial of "ZBTB24, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.