Rabbit ZBTB16 Polyclonal Antibody | anti-ZBTB16 antibody

ZBTB16 (Zinc Finger And BTB Domain-containing Protein 16, PLZF, ZNF145) (HRP)

Cat. Num. AAA6443726

• Gene Names: ZBTB16; PLZF; ZNF145
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Western Blot
• Purity: Purified by affinity chromatography.
• Synonyms: ZBTB16; Polyclonal Antibody; ZBTB16 (Zinc Finger And BTB Domain-containing Protein 16; PLZF; ZNF145) (HRP); anti-ZBTB16 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes ZBTB16. Species Crossreactivity: human, mouse, rat
• Purity/Purification: Purified by affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
• Concentration: ~1mg/ml (varies by lot)

• Applicable Applications for anti-ZBTB16 antibody: Immunohistochemistry (IHC), Western Blot (WB)
• Application Notes: IHC: 1:50-1:200; WB: 1:500-1:2000; Applications are based on unconjugated antibody.
• Immunogen: Recombinant protein corresponding to human ZBTB16.
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using ZBTB16 antibody.)

Product Categories/Family for anti-ZBTB16 antibody

Antibodies; Transcription Factors; Zinc (Ring) Finger

NCBI and Uniprot Product Information

• NCBI GI #: 66932932
• NCBI GeneID: 7704
• NCBI Accession #: NP_001018011.1
• NCBI GenBank Nucleotide #: NM_001018011.1
• UniProt Accession #: Q05516; Q8TAL4
• Molecular Weight: 61,601 Da
• NCBI Official Full Name: zinc finger and BTB domain-containing protein 16
• NCBI Official Synonym Full Names: zinc finger and BTB domain containing 16
• NCBI Official Symbol: ZBTB16
• NCBI Official Synonym Symbols: PLZF; ZNF145
• NCBI Protein Information: zinc finger and BTB domain-containing protein 16
• UniProt Protein Name: Zinc finger and BTB domain-containing protein 16
• Protein Family: Zinc finger and BTB domain-containing protein
• UniProt Gene Name: ZBTB16
• UniProt Synonym Gene Names: PLZF; ZNF145
• UniProt Entry Name: ZBT16_HUMAN

NCBI Description

This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]

Uniprot Description

Probable transcription factor. May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.