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Western Blot (WB) (Western Blot analysis of ZBTB10 in Jurkat cell lysate using ZBTB10 Rabbit pAb at dilution 1/800)

Rabbit anti-Human ZBTB10 Polyclonal Antibody | anti-ZBTB10 antibody

ZBTB10 Rabbit pAb

Gene Names
ZBTB10; RINZF
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
ZBTB10; Polyclonal Antibody; ZBTB10 Rabbit pAb; zinc finger and BTB domain containing 10; RINZF; anti-ZBTB10 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
1.7mg/ml (varies by lot)
Applicable Applications for anti-ZBTB10 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:500-1:2000
IHC-P: 1:50-1:300
Immunogen
Synthetic peptide of human ZBTB10
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western Blot analysis of ZBTB10 in Jurkat cell lysate using ZBTB10 Rabbit pAb at dilution 1/800)

Western Blot (WB) (Western Blot analysis of ZBTB10 in Jurkat cell lysate using ZBTB10 Rabbit pAb at dilution 1/800)

Immunohistochemistry (IHC)

(Immunohistochemistry of ZBTB10 in paraffin-embedded Human colorectal cancer tissue using ZBTB10 Rabbit pAb at dilution 1/100. Predicted cell location: Nucleus and Cytoplasm)

Immunohistochemistry (IHC) (Immunohistochemistry of ZBTB10 in paraffin-embedded Human colorectal cancer tissue using ZBTB10 Rabbit pAb at dilution 1/100. Predicted cell location: Nucleus and Cytoplasm)
Related Product Information for anti-ZBTB10 antibody
RINZF, also known as ZBTB10 (zinc finger and BTB domain containing protein 10), is a 847 amino acid protein that contains one BTB/POZ domain and two C2H2-type zinc fingers. Localized to the nucleus, RINZF is believed to play a role in transcriptional regulation. Specifically, RINZF is capable of binding to the CACC element of the Gastrin promoter. In this regard, RINZF competes with Sp1 for CACC binding and interferes with Sp1 transactivation, thereby regulating Gastrin gene expression. The rat RINZF protein shares 98% homology with the human RINZF protein, suggesting that RINZF is a conserved protein. Due to alternative splicing events, two RINZF isoforms exist. In addition, RINZF may be phosphorylated by ATR or ATM upon DNA damage.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
94,894 Da
NCBI Official Full Name
zinc finger and BTB domain-containing protein 10 isoform a
NCBI Official Synonym Full Names
zinc finger and BTB domain containing 10
NCBI Official Symbol
ZBTB10
NCBI Official Synonym Symbols
RINZF
NCBI Protein Information
zinc finger and BTB domain-containing protein 10; zinc finger protein RINZF; zinc finger protein RIN ZF
UniProt Protein Name
Zinc finger and BTB domain-containing protein 10
UniProt Gene Name
ZBTB10
UniProt Synonym Gene Names
RINZF; RINZFC
UniProt Entry Name
ZBT10_HUMAN

Uniprot Description

ZBTB10: May be involved in transcriptional regulation. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 8q13-q21.1

Cellular Component: nucleoplasm

Molecular Function: DNA binding; metal ion binding

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent

Research Articles on ZBTB10

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Product Notes

The ZBTB10 zbtb10 (Catalog #AAA4759710) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZBTB10 Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ZBTB10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:500-1:2000 IHC-P: 1:50-1:300. Researchers should empirically determine the suitability of the ZBTB10 zbtb10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZBTB10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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