Rabbit ZBED3 Polyclonal Antibody | anti-ZBED3 antibody

Rabbit Polyclonal to Human ZBED3

Cat. Num. AAA247759

• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Western Blot, ELISA
• Purity: Immunoaffinity Purified
• Synonyms: ZBED3; Polyclonal Antibody; Rabbit Polyclonal to Human ZBED3; Anti-ZBED3 Antibody (N-Terminus) IHC-plus; Human ZBED3; anti-ZBED3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: Human ZBED3
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.02% sodium azide
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 234

• Applicable Applications for anti-ZBED3 antibody: Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
• Application Notes: ELISA, IHC-P (5 ug/ml), WB (1 - 2 ug/ml); Usage: ZBED3 antibody can be used for detection of ZBED3 by Western blot at 1-2 ug/ml.
• Target Species: Human
• Immunogen Description: A 17 amino acid peptide from near the amino terminus of human ZBED3.
• Immunogen Type: Synthetic peptide
• Immunogen: ZBED3 antibody was raised against a 17 amino acid peptide from near the amino terminus of human ZBED3.
• Antigen Modification: N-Terminus
• Preparation and Storage: Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.

Immunohistochemistry (IHC)

(Anti-ZBED3 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Western Blot (WB)

(Western blot of ZBED3 in rat lung tissue lysate with ZBED3 antibody at (A) 1 and (B) 2 ug/ml.)

NCBI and Uniprot Product Information

• NCBI GI #: 14150185
• NCBI GeneID: 84327
• NCBI Accession #: NP_115743.1
• NCBI GenBank Nucleotide #: NM_032367.2
• UniProt Accession #: Q96IU2
• Molecular Weight: 25,132 Da
• NCBI Official Full Name: zinc finger BED domain-containing protein 3
• NCBI Official Synonym Full Names: zinc finger, BED-type containing 3
• NCBI Official Symbol: ZBED3
• NCBI Protein Information: zinc finger BED domain-containing protein 3; 2610005H11Rik; axin-interacting protein; zinc finger, BED domain containing 3
• UniProt Protein Name: Zinc finger BED domain-containing protein 3
• UniProt Gene Name: ZBED3
• UniProt Entry Name: ZBED3_HUMAN

Uniprot Description

ZBED3: Acts as a positive regulator in the activation of the canonical Wnt/beta-catenin signaling pathway by stabilizing cytoplasmic beta-catenin. Involved in transcription activation of Wnt target gene expression. Interacts with AXIN1; the interaction is direct, enhanced by protein kinase GSK3B and casein kinase CSNK1E activities and decreases GSK3B-induced beta-catenin serine and threonine phosphorylations

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 5q13.3

Cellular Component: membrane; cytosol

Molecular Function: DNA binding; metal ion binding

Biological Process: Wnt receptor signaling pathway; negative regulation of protein amino acid phosphorylation; protein stabilization; positive regulation of transcription from RNA polymerase II promoter