Rabbit YKU70 Polyclonal Antibody | anti-YKU70 antibody

Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast) YKU70 Polyclonal Antibody

• Gene Names: YKU70; HDF1; NES24
• Reactivity: Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast)
• Applications: ELISA, Western Blot
• Purity: Protein A/G
• Synonyms: YKU70; Polyclonal Antibody; Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast) YKU70 Polyclonal Antibody; YKU70 Antibody; ATP-dependent DNA helicase II subunit 1; EC 3.6.4.12; ATP-dependent DNA helicase II subunit Ku70; High affinity DNA-binding factor subunit 1; YKU70 HDF1 NES24 YMR284W YM8021.10; anti-YKU70 antibody

• Host: Rabbit
• Reactivity: Saccharomyces cerevisiae (strain ATCC 204508/S288c)(Baker's yeast)
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein A/G
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH7.4

• Applicable Applications for anti-YKU70 antibody: ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
• Immunogen: Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) YKU70 protein
• Conjugation: Non-conjugate
• Modification: Unmodified
• Deliverables: 1. 200ug recombinant immunogen protein/peptide (positive control).; 2. 1mL preimmune serum (negative control); 3. 10mg rabbit polyclonal antibody purified by Protein A/G.
• Quality Guarantee: 1. Antibody purity >90% confirmed by SDS-PAGE.; 2. Antibody titer > 1: 64,000 confirmed by ELISA; 3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
• Complementary Antibody: Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:; * 6*His Monoclonal Antibody #MBS1491670; * DYKDDDDK tag Monoclonal Antibody #MBS1493946; * GAPDH Monoclonal Antibody #MBS1495524; * GFP Monoclonal Antibody #MBS1496050; * Myc tag Monoclonal Antibody #MBS1497694; * GST Monoclonal Antibody #MBS1497871; * Sumo tag Monoclonal Antibody #MBS1498878; * Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510; * HA-Tag Monoclonal Antibody #MBS7135631; * E-Tag Monoclonal Antibody #MBS7135632; * TUBA1A Monoclonal Antibody #MBS7135645; * TUBB Monoclonal Antibody #MBS9018332
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

• NCBI GI #: 6323940
• NCBI GeneID: 855328
• NCBI Accession #: NP_014011.1
• NCBI GenBank Nucleotide #: NM_001182791.1
• UniProt Accession #: P32807; P32498; Q0P778; Q0P779; Q0P787; Q0P789; Q6B267; D6W0B1
• Molecular Weight: 70,647 Da
• NCBI Official Full Name: ATP-dependent DNA helicase YKU70
• NCBI Official Symbol: YKU70
• NCBI Official Synonym Symbols: HDF1; NES24
• NCBI Protein Information: ATP-dependent DNA helicase YKU70
• UniProt Protein Name: ATP-dependent DNA helicase II subunit 1
• UniProt Gene Name: YKU70
• UniProt Synonym Gene Names: HDF1; NES24

Uniprot Description

Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Appears to have a role in recruitment of telomerase and CDC13 to the telomere and the subsequent telomere elongation. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase. Involved in telomere maintenance. Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement. Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere. Required for mating-type switching.