Related Product Information for anti-XPR1 antibody
Xenotropic mouse leukemia viruses (X-MLVs) are broadly infectious for mammals except most of the classical strains of laboratory mice. These gammaretroviruses rely on the XPR1 receptor for entry, and the unique resistance of laboratory mice is due to two mutations in different putative XPR1extracellular loops. Cells from avian species differ in susceptibility to X-MLVs, and 2 replacement mutations in the virus-resistant chicken XPR1 distinguish it from the more permissive duck and quail receptors.
Product Categories/Family for anti-XPR1 antibody
NCBI Description
The protein encoded by this gene is a receptor for the xenotropic and polytropic classes of murine leukemia viruses. The encoded protein is involved in phosphate homeostasis by mediating phosphate export from the cell. Defects in this gene have been associated with idiopathic basal ganglia calcification-6. [provided by RefSeq, Jun 2016]
Uniprot Description
XPR1: May function in G-protein coupled signal transduction. Potential receptor for xenotropic and polytropic murine leukemia retroviruses. Belongs to the SYG1 (TC 2.A.94) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1q25.1
Cellular Component: Golgi apparatus; integral to plasma membrane; plasma membrane
Molecular Function: viral receptor activity; G-protein coupled receptor activity; transmembrane receptor activity; receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; entry of virus into host cell; response to virus
Disease: Basal Ganglia Calcification, Idiopathic, 6
Product Notes
The XPR1 xpr1 (Catalog #
AAA2563112) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The XPR1 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's XPR1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:50-1:200 ELISA: 1:1000-1:5000. Researchers should empirically determine the suitability of the XPR1 xpr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
It is sometimes possible for the material contained within the vial of
"XPR1, Polyclonal Antibody" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are
absolutely not suitable for use in any
sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a
product from AAA Biotech, you
are explicitly certifying that said products will be properly tested and used in line with
industry standard. AAA Biotech
and its authorized distribution partners reserve the right to refuse to fulfill any order if
we have any indication that a
purchaser may be intending to use a product outside of our accepted criteria.
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aspect of this datasheet at
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of any product performance
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