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SDS-Page (Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: MCF7 cells, A431 cells, Primary antibody:47467(XPNPEP3 / Antibody) at dilution 1/100, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds)

Rabbit anti-Human XPNPEP3   Polyclonal Antibody | anti-XPNPEP3 antibody

XPNPEP3 Antibody

Gene Names
XPNPEP3; APP3; ICP55; NPHPL1
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
XPNPEP3  ; Polyclonal Antibody; XPNPEP3 Antibody; APP3; NPHPL1; anti-XPNPEP3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
The antibody detects endogenous levels of total XPNPEP3 / protein.
Purity/Purification
Antigen affinity purification
Form/Format
pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
1.3 mg/mL (varies by lot)
Sequence Length
507
Applicable Applications for anti-XPNPEP3 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:200-1000
IHC: 1:25-100
Immunogen
Synthetic peptide of human XPNPEP3
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.

SDS-Page

(Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: MCF7 cells, A431 cells, Primary antibody:47467(XPNPEP3 / Antibody) at dilution 1/100, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds)

SDS-Page (Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: MCF7 cells, A431 cells, Primary antibody:47467(XPNPEP3 / Antibody) at dilution 1/100, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds)

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human lymphoma tissue using 47467(XPNPEP3 / Antibody) at dilution 1/40.(Original magnification: 200))

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human lymphoma tissue using 47467(XPNPEP3 / Antibody) at dilution 1/40.(Original magnification: 200))
Related Product Information for anti-XPNPEP3 antibody
The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known.
Product Categories/Family for anti-XPNPEP3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
57 kDa
NCBI Official Full Name
xaa-Pro aminopeptidase 3 isoform 1
NCBI Official Synonym Full Names
X-prolyl aminopeptidase 3
NCBI Official Symbol
XPNPEP3
NCBI Official Synonym Symbols
APP3; ICP55; NPHPL1
NCBI Protein Information
xaa-Pro aminopeptidase 3
UniProt Protein Name
Xaa-Pro aminopeptidase 3
UniProt Gene Name
XPNPEP3
UniProt Synonym Gene Names
X-Pro aminopeptidase 3; APP3

NCBI Description

The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known.[provided by RefSeq, Mar 2011]

Uniprot Description

Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Leu-Pro-Ala (PubMed:25609706, PubMed:28476889). Also shows low activity towards peptides with Ala or Ser at the P1 position (PubMed:28476889).

Research Articles on XPNPEP3

Similar Products

Product Notes

The XPNPEP3 xpnpep3 (Catalog #AAA9430449) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The XPNPEP3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's XPNPEP3   can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:200-1000 IHC: 1:25-100. Researchers should empirically determine the suitability of the XPNPEP3 xpnpep3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "XPNPEP3  , Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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