Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Immunogen
XIAP antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human BIRC4, different from the related Rabbit sequence by two amino acids, as the immunogen
Preparation and Storage
Store at 4 degree C for short term storage. For long term storage aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin embedded section of Human Intestinal Cancer Tissue)
Western Blot (WB)
(Lane 1: SMMC Cell Lysate, Lane 2: HELA Cell Lysate, Lane 3: A431 Cell Lysate)
Related Product Information for anti-XIAP antibody
IAP (inhibitor of apoptosis protein) is an evolutionarily conserved inhibitory factor of apoptosis. IAP directly binds to caspase which plays the central role in operation of apoptosis and inhibits it. Human XIAP (Xchromosomelinked inhibitor of apoptosis protein) is known as one of the IAP family and binds to caspase 3, 7, and 9 directly and inhibits their functions. XIAP has three BIR (baculovirus IAP repeat) domains. It is confirmed that BIR2 domain binds to caspase 3 and 7, and BIR3 domain binds to caspase 9. Also it is known that the RING finger domain has a ubiquitin ligase activity and is associated with ubiquitination of caspase.
The XIAP (Catalog #AAA5312824) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's XIAP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the XIAP for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
It is sometimes possible for the material contained within the vial of
"XIAP, Polyclonal Antibody" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are
absolutely not suitable for use in any
sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a
product from AAA Biotech, you
are explicitly certifying that said products will be properly tested and used in line with
industry standard. AAA Biotech
and its authorized distribution partners reserve the right to refuse to fulfill any order if
we have any indication that a
purchaser may be intending to use a product outside of our accepted criteria.
Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech
cannot be held
responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any
aspect of this datasheet at
any time and without notice. It is the responsibility of the customer to inform AAA Biotech
of any product performance
issues observed or experienced within 30 days of receipt of said product. To see additional
details on this or any of our
other policies, please see our Terms & Conditions page.