Immunohistochemistry (IHC)
(Immunochemical staining of human WNT7A in human skeletal muscle with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human Wnt7a Polyclonal Antibody | anti-Wnt7a antibody
Anti-Wnt7a Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
Wnt7a; Polyclonal Antibody; Anti-Wnt7a Antibody; Rabbit Polyclonal; Wnt7a Antibody; Rabbit PAb; Antigen Affinity Purified; wingless-type MMTV integration site family; member 7A; anti-Wnt7a antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human Wnt7a
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-Wnt7a antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:50-1:200
Immunogen
E Coli-derived Human Wnt7a fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human Wnt7a fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human WNT7A in human skeletal muscle with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human WNT7A in human skeletal muscle with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-Wnt7a antibody
Wnt7a, a 39Kd secreted glycoprotein composed of 349 amino acids, is a member of the Wnt family and has been reported to be involved in the carcinogenesis and progression of many types of human cancer. Wnt7a could be used as a potential marker and target for gastric cancer (GC) management. Wnt7a is a known tumor suppressor gene in non-small cell lung cancer that regulates normal cellular proliferation and differentiation. Loss of Wnt7a expression may contribute to the carcinogenesis and tumor progression of colorectal adenocarcinoma and maybe a new prognostic marker of colorectal adenocarcinoma. WNT7A, an important ligand of Wnt/beta-catenin signaling pathways, has a controversial role in tumor development.
Product Categories/Family for anti-Wnt7a antibody
References
Wu DJ, et al. (2018) High expression of wnt7a predicts poor prognosis and promote tumor metastasis in pancreatic ductal adenocarcinoma. Sci Rep 8 (1): 15792.Liu Y, et al. (2019) Wnt7a, frequently silenced by cpg methylation, inhibits tumor growth and metastasis via suppressing epithelial-mesenchymal transition in gastric cancer. J Cell Biochem 120 (10): 18142-18151.Lan L, et al. (2019) Wnt7a overexpression inhibits growth and migration of hepatocellular carcinoma via the beta-catenin independent pathway. Biomed Res Int 2019 3605950.Jang SM, et al. (2018) Loss of wnt7a expression correlates with tumor progression and poor prognosis in colorectal carcinoma. Int J Clin Exp Pathol 11 (10): 4967-4976.
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Product Notes
The Wnt7a (Catalog #AAA8108060) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Wnt7a Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Wnt7a can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:50-1:200. Researchers should empirically determine the suitability of the Wnt7a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Wnt7a, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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