Testing Data
(Primary: Anti- Wnt11 at 1/1000 dilution)
Rabbit Wnt11 Polyclonal Antibody | anti-Wnt11 antibody
Wnt11 Polyclonal Antibody
Gene Names
WNT11; HWNT11
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit
Applications
Western Blot
Purity
affinity purified by Protein A
Synonyms
Wnt11; Polyclonal Antibody; Wnt11 Polyclonal Antibody; HWNT11; Protein Wnt-11; Wingless-related MMTV integration site 11; Wingless-type MMTV integration site family; member 1; member 11; member 11B; wnt-11; wnt11b.WNT11_HUMAN; anti-Wnt11 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit
Clonality
Polyclonal
Specificity
Wnt11 Polyclonal Antibody detects endogenous levels of Wnt11 protein.
Purity/Purification
affinity purified by Protein A
Form/Format
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Applicable Applications for anti-Wnt11 antibody
Western Blot (WB)
Application Notes
WB: 1:500-2000
Immunogen
KLH conjugated synthetic peptide derived from human Wnt11:151-250/354
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Testing Data
(Primary: Anti- Wnt11 at 1/1000 dilution)
Testing Data
(Primary: Anti- Wnt11 at 1/1000 dilution)
Testing Data
(Primary: Anti- Wnt11 at 1/1000 dilution)
Testing Data
(Primary: Anti- Wnt11 at 1/1000 dilution)
Related Product Information for anti-Wnt11 antibody
The Wnt genes belong to a family of protooncogenes with at least 13 known members that are expressed in species ranging from Drosophila to man. The name Wnt denotes the relationship of this family to the Drosophila segment polarity gene "wingless" and to its vertebrate ortholog, Int-1, a mouse proto-oncogene. Transcription of Wnt family genes appears to be developmentally regulated in a precise temporal and spatial manner. The Wnt genes encode cysteine-rich putative glycoproteins which have features typical of secreted growth factors. Wnt-11 is expressed in the tips of ureteric buds and in the perichondrium, a stem cell-like layer that surrounds the future bones and directs their growth and regeneration. Wnt-11 activity is required for cells to undergo correct convergent extension movements during gastrulation. Human Wnt-11 is also expressed in the lung mesenchyme, the urorectal septum, the urogenital folds, the labioscrotal swellings, and the cortex of the adrenal gland. Unlike other Wnt family members, Wnt-11 is not expressed in the neuroepithelium of the central nervous system. Wnt-11, along with Wnt-8c, is ex-pressed in the posterior region of the chick embryo in the caudal paraxial mesoderm that underlies the prospective caudal neural plate. The gene which encodes Wnt-11 maps to human chromosome 11q13.5.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
39,179 Da
NCBI Official Full Name
WNT11
NCBI Official Synonym Full Names
Wnt family member 11
NCBI Official Symbol
WNT11
NCBI Official Synonym Symbols
HWNT11
NCBI Protein Information
protein Wnt-11
UniProt Protein Name
Protein Wnt-11
Protein Family
UniProt Gene Name
WNT11
NCBI Description
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 97%, 85%, and 63% amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome. [provided by RefSeq, Jul 2008]
Uniprot Description
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
Research Articles on Wnt11
Similar Products
Product Notes
The Wnt11 wnt11 (Catalog #AAA3005587) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Wnt11 Polyclonal Antibody reacts with Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit and may cross-react with other species as described in the data sheet. AAA Biotech's Wnt11 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-2000. Researchers should empirically determine the suitability of the Wnt11 wnt11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Wnt11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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