Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human ovarian cancer using MBS1497552 at dilution of 1:100)
Rabbit anti-Human WHSC1L1 Polyclonal Antibody | anti-WHSC1L1 antibody
WHSC1L1 Antibody
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human ovarian cancer using MBS1497552 at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human ovarian cancer using MBS1497552 at dilution of 1:100)
NCBI and Uniprot Product Information
NCBI Description
This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. Two alternatively spliced variants have been described. [provided by RefSeq, May 2015]
Uniprot Description
WHSC1L1: is related to the Wolf-Hirschhorn syndrome candidate-1 protein containing PWWP (proline-tryptophan-tryptophan-proline) domains. The function of the protein has not been determined. Two alternatively spliced isoforms have been described.
Protein type: Oncoprotein; Histone-binding; EC 2.1.1.43; Amino Acid Metabolism - lysine degradation; Methyltransferase; Methyltransferase, protein lysine
Chromosomal Location of Human Ortholog: 8p11.2
Cellular Component: chromosome; nucleoplasm; nucleus
Molecular Function: histone lysine N-methyltransferase activity (H3-K27 specific); histone lysine N-methyltransferase activity (H3-K4 specific); histone-lysine N-methyltransferase activity; protein binding; zinc ion binding
Biological Process: establishment and/or maintenance of chromatin architecture; histone H3-K4 methylation; histone methylation; negative regulation of transcription, DNA-dependent; transcription, DNA-dependent
Disease: Leukemia, Acute Myeloid
Research Articles on WHSC1L1
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Product Notes
The WHSC1L1 whsc1l1 (Catalog #AAA1497552) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The WHSC1L1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's WHSC1L1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the WHSC1L1 whsc1l1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "WHSC1L1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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