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Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/40.)

Rabbit anti-Human WDR45B Polyclonal Antibody | anti-WDR45B antibody

WDR45B Antibody

Gene Names
WDR45B; WIPI3; WDR45L; WIPI-3
Reactivity
Human
Applications
Immunohistochemistry
Purity
Antigen affinity purification.
Synonyms
WDR45B; Polyclonal Antibody; WDR45B Antibody; WIPI3; WDR45L; WIPI-3; anti-WDR45B antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total WDR45B protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
2.5 mg/ml (varies by lot)
Sequence Length
344
Applicable Applications for anti-WDR45B antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1:30-1:150
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide of human WD repeat domain 45B
Target Name
WDR45B
Preparation and Storage
Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/40.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/40.)
Related Product Information for anti-WDR45B antibody
This gene encodes a member of the WIPI or SVP1 family of WD40 repeat-containing proteins. The protein contains seven WD40 repeats that are thought to fold into a beta-propeller structure that mediates protein-protein interactions, and a conserved motif for interaction with phospholipids. The human genome contains several pseudogenes of this gene.
Product Categories/Family for anti-WDR45B antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,122 Da
NCBI Official Full Name
WD repeat domain phosphoinositide-interacting protein 3
NCBI Official Synonym Full Names
WD repeat domain 45B
NCBI Official Symbol
WDR45B
NCBI Official Synonym Symbols
WIPI3; WDR45L; WIPI-3
NCBI Protein Information
WD repeat domain phosphoinositide-interacting protein 3
UniProt Protein Name
WD repeat domain phosphoinositide-interacting protein 3
UniProt Gene Name
WDR45B
UniProt Synonym Gene Names
WDR45L; WIPI3; WIPI-3; WDR45-like protein
UniProt Entry Name
WIPI3_HUMAN

NCBI Description

This gene encodes a member of the WIPI or SVP1 family of WD40 repeat-containing proteins. The protein contains seven WD40 repeats that are thought to fold into a beta-propeller structure that mediates protein-protein interactions, and a conserved motif for interaction with phospholipids. The human genome contains several pseudogenes of this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

WDR45B: an ubiquitously expressed WD40 repeat protein. Up-regulated in a variety of tumor tissues including ovarian and uterine cancers. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 17q25.3

Cellular Component: extrinsic to membrane; pre-autophagosomal structure membrane; cytosol

Molecular Function: phosphatidylinositol 3-phosphate binding

Biological Process: protein amino acid lipidation; mitochondrion degradation; autophagic vacuole formation; cellular response to nitrogen starvation

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Product Notes

The WDR45B wdr45b (Catalog #AAA9410896) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The WDR45B Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's WDR45B can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:30-1:150. Researchers should empirically determine the suitability of the WDR45B wdr45b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "WDR45B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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