Rabbit anti-Human WDR35 Polyclonal Antibody | anti-WDR35 antibody

WDR35 Antibody

Cat. Num. AAA9403210

• Gene Names: WDR35; CED2; IFTA1; SRTD7; IFT121
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry
• Purity: Affinity chromatography purified via peptide column
• Synonyms: WDR35; Polyclonal Antibody; WDR35 Antibody; WD repeat-containing protein 35; CED2; anti-WDR35 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: WDR35 antibody is human specific.
• Purity/Purification: Affinity chromatography purified via peptide column
• Form/Format: PBS containing 0.02% sodium azide.
• Sequence Length: 1181

• Applicable Applications for anti-WDR35 antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Immunogen Type: Peptide
• Immunogen Description: 16 amino acid peptide near the amino terminus of human WDR35.
• Target Name: WDR35
• Preparation and Storage: Store at 4 degree C for three months and -20 degree C, stable for up to one year.

Immunohistochemistry (IHC)

(Immunohistochemistry of WDR35 in human testis tissue with WDR35 antibody at 5 ug/ml.)

Product Categories/Family for anti-WDR35 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 55743161
• NCBI GeneID: 57539
• NCBI Accession #: NP_001006658
• NCBI GenBank Nucleotide #: NM_001006657.1
• Molecular Weight: 132,308 Da
• NCBI Official Full Name: WD repeat-containing protein 35 isoform 1
• NCBI Official Synonym Full Names: WD repeat domain 35
• NCBI Official Symbol: WDR35
• NCBI Official Synonym Symbols: CED2; IFTA1; SRTD7; IFT121
• NCBI Protein Information: WD repeat-containing protein 35
• UniProt Protein Name: WD repeat-containing protein 35
• Protein Family: WD repeat-containing protein
• UniProt Gene Name: WDR35
• UniProt Synonym Gene Names: IFT121; KIAA1336
• UniProt Entry Name: WDR35_HUMAN

NCBI Description

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Two patients with Sensenbrenner syndrome / cranioectodermal dysplasia (CED) were identified with mutations in this gene, consistent with a possible ciliary function.[provided by RefSeq, Sep 2010]

Uniprot Description

WDR35: a WD40 repeat protein. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. Two alternatively spliced human isoforms have been described.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 2p24.1

Cellular Component: centrosome; axoneme

Biological Process: organelle organization and biogenesis; cilium biogenesis

Disease: Cranioectodermal Dysplasia 2; Short-rib Thoracic Dysplasia 7 With Or Without Polydactyly