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Western Blot (WB) (Western blot analysis of WDR1 Antibody (C-term) in CEM cell line lysates (35ug/lane).WDR1 (arrow) was detected using the purified Pab.)

Rabbit WDR1 Polyclonal Antibody | anti-WDR1 antibody

WDR1 Antibody (C-term)

Gene Names
WDR1; AIP1; NORI-1; HEL-S-52
Reactivity
Human (Predicted Reactivity: Bovine)
Applications
Western Blot, ELISA
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
WDR1; Polyclonal Antibody; WDR1 Antibody (C-term); WD repeat-containing protein 1; Actin-interacting protein 1; AIP1; NORI-1; anti-WDR1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This WDR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 548-577 amino acids from the C-terminal region of human WDR1.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
548-577
Sequence Length
466
Applicable Applications for anti-WDR1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of WDR1 Antibody (C-term) in CEM cell line lysates (35ug/lane).WDR1 (arrow) was detected using the purified Pab.)

Western Blot (WB) (Western blot analysis of WDR1 Antibody (C-term) in CEM cell line lysates (35ug/lane).WDR1 (arrow) was detected using the purified Pab.)
Related Product Information for anti-WDR1 antibody
WDR1 is a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. This protein may help induce the disassembly of actin filaments.
Product Categories/Family for anti-WDR1 antibody
References
McArdle,P.F., et.al., Arthritis Rheum. 58 (9), 2874-2881 (2008)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
66194
NCBI Official Full Name
WD repeat-containing protein 1 isoform 2
NCBI Official Synonym Full Names
WD repeat domain 1
NCBI Official Symbol
WDR1
NCBI Official Synonym Symbols
AIP1; NORI-1; HEL-S-52
NCBI Protein Information
WD repeat-containing protein 1
UniProt Protein Name
WD repeat-containing protein 1
UniProt Gene Name
WDR1
UniProt Synonym Gene Names
AIP1
UniProt Entry Name
WDR1_HUMAN

NCBI Description

This gene encodes a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. The encoded protein may help induce the disassembly of actin filaments. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

WDR1: a WD40 repeat cytoskeletal protein that induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. Three alternatively spliced human isoforms have been described.

Protein type: Actin-binding

Chromosomal Location of Human Ortholog: 4p16.1

Cellular Component: cell projection; cytoplasm; extracellular region; podosome; actin filament; cell junction; cytosol

Molecular Function: actin binding

Biological Process: platelet activation; sensory perception of sound; platelet degranulation; regulation of oligodendrocyte differentiation; blood coagulation

Research Articles on WDR1

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Product Notes

The WDR1 wdr1 (Catalog #AAA9212911) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 548-577. The WDR1 Antibody (C-term) reacts with Human (Predicted Reactivity: Bovine) and may cross-react with other species as described in the data sheet. AAA Biotech's WDR1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the WDR1 wdr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "WDR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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