Goat anti-Mouse VSIG2 Polyclonal Antibody | anti-VSIG2 antibody

VSIG2 (V-set and Ig Domain-containing Protein 2, CTM, CT-like Protein)

Cat. Num. AAA618274

• Gene Names: VSIG2; CTH; CTXL; 2210413P10Rik
• Reactivity: Mouse
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: VSIG2; Polyclonal Antibody; VSIG2 (V-set and Ig Domain-containing Protein 2; CTM; CT-like Protein); Anti -VSIG2 (V-set and Ig Domain-containing Protein 2; anti-VSIG2 antibody

• Host: Goat
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes mouse VSIG2.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a lyophilized powder in PBS, 5% trehalose. Reconstitute with 500ul sterile 40-50% glycerol, PBS.

• Applicable Applications for anti-VSIG2 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Direct ELISA and Western Blot.; Dilution: Direct ELISA: 0.5-1.0ug/ml detection limit for rmVSIG2 is ~ 1ng/well.; Western Blot: 0.1-0.2ug/ml detection limit for rmVSIG2 is ~ 1 ng/lane under non-reducing and reducing conditions.
• Immunogen: NS0-derived rmVSIG2 isoform 1 extracellular domain. (aa 25 - 244)
• Preparation and Storage: Lyophilized powder may be stored at -20 degree C. Reconstitute to nominal volume by adding sterile 40-50% glycerol, aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Related Product Information for anti-VSIG2 antibody

VSIG2 (V-set and Ig domain-containing protein 2; also CTM and CT-like protein) is presumably a 50-60kD member of the CTX family of Ig-Superfamily proteins. It shows expression in stomach and prostate by Northern blot, and likely participates in cell adhesion. Mouse VSIG2 precursor is 328 amino acids (aa) in length. It is a type I transmembrane (glyco)protein that contains a 220 aa extracellular domain (ECD) (aa 25-244) and a 63 aa cytoplasmic region. The ECD contains one V-type (aa 25-138) and one C2-type Ig-like domain (aa 145-234). Over aa 25-244, mouse VSIG2 is 94%, 83% and 85% aa identical to rat, canine and human VSIG2, respectively. Two potential splice variants exist, one that shows a deletion of aa 305-328 and a second that shows a deletion of aa 144-236.

Product Categories/Family for anti-VSIG2 antibody

Antibodies; Abs to Carbohydrates; Glycoproteins

NCBI and Uniprot Product Information

• NCBI GI #: 21361429
• NCBI GeneID: 23584
• NCBI Accession #: NP_055127.2
• NCBI GenBank Nucleotide #: NM_014312.3
• UniProt Accession #: Q96IQ7; O95791; Q9NX42
• Molecular Weight: 34,348 Da
• NCBI Official Full Name: V-set and immunoglobulin domain-containing protein 2
• NCBI Official Synonym Full Names: V-set and immunoglobulin domain containing 2
• NCBI Official Symbol: VSIG2
• NCBI Official Synonym Symbols: CTH; CTXL; 2210413P10Rik
• NCBI Protein Information: V-set and immunoglobulin domain-containing protein 2; CT-like protein; OTTHUMP00000197171; OTTHUMP00000197172; cortical thymocyte-like protein; cortical thymocyte receptor (X. laevis CTX) like
• UniProt Protein Name: V-set and immunoglobulin domain-containing protein 2
• Protein Family: V-set and immunoglobulin domain-containing protein
• UniProt Gene Name: VSIG2
• UniProt Synonym Gene Names: CTH; CTXL
• UniProt Entry Name: VSIG2_HUMAN

Uniprot Description

VSIG2: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q24

Cellular Component: membrane; integral to plasma membrane