VSIG2 recombinant protein

VSIG2 Protein, Human, Recombinant (His Tag)

Cat. Num. AAA8120847

• Gene Names: VSIG2; CTH; CTXL; 2210413P10Rik
• Purity: >95% as determined by SDS-PAGE
• Synonyms: VSIG2; VSIG2 Protein; Human; Recombinant (His Tag); Human VSIG2/CTXL Protein (His Tag); 2210413P10Rik Protein; CTH Protein; CTXL Protein; V-set and immunoglobulin domain containing 2; VSIG2 recombinant protein

• Host: HEK293 Cells
• Purity/Purification: >95% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Met1-Ala243

• Species: Human
• Endotoxin: <1.0EU per ug of the protein as determined by the LAL method
• Predicted N Terminal: Val 24
• Tag: C-His
• Protein Construction: A DNA sequence encoding the human VSIG2 isoform 1 (Q96IQ7-1) extracellular domain (Met 1-Ala 243) was fused with a polyhistidine tag at the C-terminus.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

SDS-Page

Related Product Information for VSIG2 recombinant protein

Background: V-set and immunoglobulin domain-containing protein 2, also known as cortical thymocyte-like protein, CT-like protein and VSIG2, is a single-pass type I membrane protein that contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. VSIG2 is highly expressed in stomach, colon, prostate, trachea and thyroid glands and weakly in bladder and lung. V-set domains are Ig-like domains resembling the antibody variable domain. V-set domains are found in diverse protein families, including immunoglobulin light and heavy chains; in several T-cell receptors such as CD2 (Cluster of Differentiation 2), CD4, CD8, and CD86; in myelin membrane adhesion molecules; in junction adhesion molecules (JAM); in tyrosine-protein kinase receptors; and in the programmed cell death protein 1 (PD1).

References

Satow Y, et al.,1986, J. Mol. Biol. 190(4): 593-604. Kariuki,S.N. et al., 2010, Arthritis Res Ther. 12 (4):R151.

NCBI and Uniprot Product Information

• NCBI GI #: 1050112776
• NCBI GeneID: 23584
• NCBI Accession #: NP_001316849.1
• NCBI GenBank Nucleotide #: NM_001329920.1
• UniProt Accession #: Q96IQ7; O95791; Q9NX42
• Molecular Weight: 29,829 Da
• NCBI Official Full Name: V-set and immunoglobulin domain-containing protein 2 isoform 2
• NCBI Official Synonym Full Names: V-set and immunoglobulin domain containing 2
• NCBI Official Symbol: VSIG2
• NCBI Official Synonym Symbols: CTH; CTXL; 2210413P10Rik
• NCBI Protein Information: V-set and immunoglobulin domain-containing protein 2
• UniProt Protein Name: V-set and immunoglobulin domain-containing protein 2
• Protein Family: V-set and immunoglobulin domain-containing protein
• UniProt Gene Name: VSIG2
• UniProt Synonym Gene Names: CTH; CTXL; CT-like protein

Uniprot Description

Enzyme and pathway databasesBioCyc Collection of Pathway/Genome DatabasesMore...BioCyciZFISH:ENSG00000019102-MONOMER. Protein family/group databasesMEROPS protease databaseMore...MEROPSiI43.001.