Rabbit anti-Human VPS53 Polyclonal Antibody | anti-VPS53 antibody
VPS53 Rabbit pAb
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein with sequence similarity to the yeast Vps53p protein. Vps53p is involved in retrograde vesicle trafficking in late Golgi. [provided by RefSeq, Jul 2008]
Uniprot Description
VPS53: May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Belongs to the VPS53 family. 4 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 17p13.3
Cellular Component: Golgi apparatus; perinuclear region of cytoplasm; endosome membrane
Molecular Function: protein binding
Biological Process: protein transport; retrograde transport, endosome to Golgi
Disease: Pontocerebellar Hypoplasia, Type 2e
Research Articles on VPS53
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Product Notes
The VPS53 vps53 (Catalog #AAA8537813) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The VPS53 Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's VPS53 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 200-1000. Researchers should empirically determine the suitability of the VPS53 vps53 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VPS53, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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