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Western Blot (WB) (All lanes : Anti-VPS37C Antibody (Center) at 1:1000 dilutionLane 1: Raji whole cell lysateLane 2: Hela whole cell lysateLane 3: HT-29 whole cell lysateLane 4: PC-12 whole cell lysateLane 5: PC-3 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 39 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Rabbit anti-Human, Rat VPS37C Polyclonal Antibody | anti-VPS37C antibody

VPS37C Antibody (Center)

Reactivity
Human, Rat
Applications
Western Blot, ELISA
Synonyms
VPS37C; Polyclonal Antibody; VPS37C Antibody (Center); Vacuolar protein sorting-associated protein 37C; hVps37C; ESCRT-I complex subunit VPS37C; PML39; anti-VPS37C antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
Ig
Specificity
This VPS37C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-169 amino acids from the Central region of human VPS37C.
Sequence Length
355
Applicable Applications for anti-VPS37C antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000
Antigen Source
Human
Antigen Region
142-169
Antigen Type
Synthetic Peptide
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(All lanes : Anti-VPS37C Antibody (Center) at 1:1000 dilutionLane 1: Raji whole cell lysateLane 2: Hela whole cell lysateLane 3: HT-29 whole cell lysateLane 4: PC-12 whole cell lysateLane 5: PC-3 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 39 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (All lanes : Anti-VPS37C Antibody (Center) at 1:1000 dilutionLane 1: Raji whole cell lysateLane 2: Hela whole cell lysateLane 3: HT-29 whole cell lysateLane 4: PC-12 whole cell lysateLane 5: PC-3 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 39 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-VPS37C antibody
Description: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Background: VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies (Eastman et al., 2005 [PubMed 15509564]).
Product Categories/Family for anti-VPS37C antibody
References
Rose, J. Phd, et al. Mol. Med. (2010). Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009). Eastman, S.W., et al. J. Biol. Chem. 280(1):628-636(2005).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38659
NCBI Official Full Name
vacuolar protein sorting-associated protein 37C
NCBI Official Synonym Full Names
VPS37C subunit of ESCRT-I
NCBI Official Symbol
VPS37C
NCBI Protein Information
vacuolar protein sorting-associated protein 37C
UniProt Protein Name
Vacuolar protein sorting-associated protein 37C
UniProt Gene Name
VPS37C
UniProt Synonym Gene Names
PML39; hVps37C
UniProt Entry Name
VP37C_HUMAN

NCBI Description

VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies (Eastman et al., 2005 [PubMed 15509564]).[supplied by OMIM, Mar 2008]

Uniprot Description

VPS37C: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. Belongs to the VPS37 family.

Chromosomal Location of Human Ortholog: 11q12.2

Cellular Component: late endosome membrane; endosome membrane

Molecular Function: protein binding; calcium-dependent protein binding

Biological Process: protein transport; viral reproduction; viral protein processing; viral infectious cycle; virus assembly; endosome transport

Research Articles on VPS37C

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Product Notes

The VPS37C vps37c (Catalog #AAA9232101) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The VPS37C Antibody (Center) reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's VPS37C can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000. Researchers should empirically determine the suitability of the VPS37C vps37c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VPS37C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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