Testing Data
Rabbit VPS37A Polyclonal Antibody | anti-VPS37A antibody
VPS37A Antibody
Gene Names
VPS37A; HCRP1; PQBP2; SPG53
Reactivity
HumanPredicted: Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Synonyms
VPS37A; Polyclonal Antibody; VPS37A Antibody; anti-VPS37A antibody
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Predicted: Mouse, Rat
Clonality
Polyclonal
Form/Format
Purified by protein affinity column containing 1% BSA and 0.02% NaN3
Sequence Length
372
Applicable Applications for anti-VPS37A antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:20,000-1:80,000
WB: 1:200-1:1,000
IHC: 1:100-1:500
WB: 1:200-1:1,000
IHC: 1:100-1:500
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Testing Data
Testing Data
Testing Data
Testing Data
Related Product Information for anti-VPS37A antibody
Rabbit polyclonal VPS37A(1) antibody was raised against a recombinate human VPS37A protein 202-389aa (BC067754).
References
(1) Zivony-Elboum, Y., Westbroek, W., Kfir, N., et al. A founder mutation in Vps37A causes autosomal recessive complex hereditary spastic paraparesis. J. Med. Genet. 49 (7), 462-472 (2012).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
20,891 Da
NCBI Official Full Name
vacuolar protein sorting-associated protein 37A isoform 2
NCBI Official Synonym Full Names
VPS37A, ESCRT-I subunit
NCBI Official Symbol
VPS37A
NCBI Official Synonym Symbols
HCRP1; PQBP2; SPG53
NCBI Protein Information
vacuolar protein sorting-associated protein 37A
UniProt Protein Name
Vacuolar protein sorting-associated protein 37A
Protein Family
UniProt Gene Name
VPS37A
UniProt Synonym Gene Names
HCRP1; hVps37A
NCBI Description
This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012]
Uniprot Description
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
Research Articles on VPS37A
1. HCRP1 is a negative regulator in prostate cancer progression, metastasis and multi-drug resistance.
Similar Products
Product Notes
The VPS37A vps37a (Catalog #AAA8527190) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The VPS37A Antibody reacts with Human Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's VPS37A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:20,000-1:80,000 WB: 1:200-1:1,000 IHC: 1:100-1:500. Researchers should empirically determine the suitability of the VPS37A vps37a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VPS37A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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