Rabbit VPS35 Polyclonal Antibody | anti-VPS35 antibody
VPS35
Gene Names
VPS35; MEM3; PARK17
Reactivity
HumanPredicted: Rat, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Purified By Antigen Affinity Column
Synonyms
VPS35; Polyclonal Antibody; MEM3; PARK17; anti-VPS35 antibody
Host
Rabbit
Reactivity
Human
Predicted: Rat, Mouse
Predicted: Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified By Antigen Affinity Column
Form/Format
Already dissolved in sterile H2O with 1% BSA and 0.02% NaN3 and 50% Glycerol.
Sequence Length
2682
Applicable Applications for anti-VPS35 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:20,000-80,000
WB: 1:200-1,000
IHC: 1:100-500
WB: 1:200-1,000
IHC: 1:100-500
Immunogen
Recombinant fragment corresponding to 491-697aa of human VPS35.
Cellular Localization
Cytoplasm, Endosome, Membrane
Related Product Information for anti-VPS35 antibody
Vacuolar protein sorting-associated protein 35
References
Sudhaman S, Behari M, Govindappa ST, et al. VPS35 and EIF4G1 mutations are rare in Parkinson's disease among Indians. Neurobiol Aging. 34 (10):2442 (2013)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
47kDa
NCBI Official Full Name
Homo sapiens vacuolar protein sorting 35 homolog (S. cerevisiae), mRNA
NCBI Official Synonym Full Names
VPS35 retromer complex component
NCBI Official Symbol
VPS35
NCBI Official Synonym Symbols
MEM3; PARK17
NCBI Protein Information
vacuolar protein sorting-associated protein 35
Protein Family
NCBI Description
This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. [provided by RefSeq, Jul 2008]
Research Articles on VPS35
Similar Products
Product Notes
The VPS35 (Catalog #AAA8560546) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The VPS35 reacts with Human Predicted: Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's VPS35 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:20,000-80,000 WB: 1:200-1,000 IHC: 1:100-500. Researchers should empirically determine the suitability of the VPS35 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VPS35, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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