Rabbit VPS24 Polyclonal Antibody | anti-VPS24 antibody

VPS24 antibody

Cat. Num. AAA5301241

• Applications: ELISA, Immunohistochemistry, Immunofluorescence, Western Blot
• Purity: VPS24 antibody was purified by Antigen Affinity chromatography
• Synonyms: VPS24; Polyclonal Antibody; VPS24 antibody; Polyclonal VPS24; Anti-VPS24; Vacuolar Protein Sorting 24 Homolog; Vps24; Cgi 149; Chmp3; Nedf; anti-VPS24 antibody

• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: VPS24 antibody was purified by Antigen Affinity chromatography
• Form/Format: Supplied in PBS buffer with 0.02% Sodium Azide and 50% Glycerol, pH 7.3
• Sequence Length: 224

• Applicable Applications for anti-VPS24 antibody: ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blot (WB)
• Biological Significance: VPS24 is a probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.
• Cross-Reactivity: Human, Mouse, Rat
• Immunogen: VPS24 antibody was raised in Rabbit using Human VPS24 as the immunogen
• Preparation and Storage: Store at 4 degree C for short term storage and -20 degree C for long term storage. Avoid repeat freeze/thaw cycles

Related Product Information for anti-VPS24 antibody

Rabbit polyclonal VPS24 antibody

Product Categories/Family for anti-VPS24 antibody

Cell Biology; Purified Polyclonal Antibodies

NCBI and Uniprot Product Information

• NCBI GI #: 486052
• UniProt Accession #: P36095; D6VXP5
• Molecular Weight: 26,242 Da
• NCBI Official Full Name: VPS24
• UniProt Protein Name: Vacuolar protein-sorting-associated protein 24
• Protein Family: Vacuolar protein sorting-associated protein
• UniProt Gene Name: VPS24
• UniProt Synonym Gene Names: DID3
• UniProt Entry Name: VPS24_YEAST

Uniprot Description

Class E VPS protein implicated in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles. The lumenal sequestrated membrane proteins will be targeted into the vacuole after fusion of the endosome with the vacuole. Acts a component of the ESCRT-III complex, which appears to be critical for late steps in MVB sorting, such as membrane invagination and final cargo sorting and recruitment oflate-acting components of the sorting machinery. The MVB pathway requires the sequential function of ESCRT-O, -I,-II and -III complex assemblies. The DID4/VPS2-VPS24 subcomplex is required for the VPS4-dependent dissociation of ESCRT-III.