Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human brain using MBS7605629 (VEZT antibody) at dilution of 1:100)
Rabbit VEZT Polyclonal Antibody | anti-VEZT antibody
VEZT Rabbit Polyclonal
Immunogen Affinity Purified
Immunogen Affinity Purified
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human brain using MBS7605629 (VEZT antibody) at dilution of 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human brain using MBS7605629 (VEZT antibody) at dilution of 1:100)
Western Blot (WB)
(human brain tissue were subjected to SDS PAGE followed by western blot with MBS7605629 (VEZT antibody) at dilution of 1:500)
Western Blot (WB)
(human brain tissue were subjected to SDS PAGE followed by western blot with MBS7605629 (VEZT antibody) at dilution of 1:500)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a transmembrane protein which has been localized to adherens junctions and shown to bind to myosin VIIA. Examination of expression of this gene in gastric cancer tissues have shown that expression is decreased which appears to be related to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific microRNA to a target sequence in the 3' UTR of the transcripts. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]
Uniprot Description
VEZATIN: Plays a pivotal role in the establishment of adherens junctions and their maintenance in adult life. In case of Listeria infection, promotes bacterial internalization by participating in myosin VIIa recruitment to the entry site. Belongs to the vezatin family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 12q22
Cellular Component: acrosome; adherens junction; cytoplasm; integral to membrane; nucleoplasm; plasma membrane
Molecular Function: myosin binding
Biological Process: cell-cell adhesion
Research Articles on VEZT
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Product Notes
The VEZT vezt (Catalog #AAA7605629) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The VEZT Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's VEZT can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the VEZT vezt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VEZT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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