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Rabbit Vesicular Acetylcholine Transporter Polyclonal Antibody | anti-SLC18A3 antibody

Vesicular Acetylcholine Transporter antibody

Gene Names
SLC18A3; VACHT
Applications
Immunohistochemistry
Synonyms
Vesicular Acetylcholine Transporter; Polyclonal Antibody; Vesicular Acetylcholine Transporter antibody; Polyclonal Vesicular Acetylcholine Transporter; Anti Vesicular Acetylcholine Transporter; VAChT; anti-SLC18A3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Form/Format
Supplied in lyophilized form. Dissolve the antiserum in 50 - 100 ul distilled water and dilute further in 0.1 M PBS with 1% BSA and 0.1% Na-azide
Sequence Length
532
Applicable Applications for anti-SLC18A3 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:800 - 1:1200
Biological Significance
The Vesicular acetylcholine transporter (VAChT) is a neurotransmitter transporter which is responsible for loading acetylcholine (ACh) into secretory organelles in neurons making acetylcholine available for secretion.
Cross-Reactivity
To be determined by the end user
Immunogen
Vesicular Acetylcholine Transporter antibody was raised in rabbit using synthetic peptide from the C-terminus of human VAChT conjugated to BSA as the immunogen.
Preparation and Storage
Store at 2-8 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-SLC18A3 antibody
Rabbit polyclonal Vesicular Acetylcholine Transporter antibody
Product Categories/Family for anti-SLC18A3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
56,903 Da
NCBI Official Full Name
vesicular acetylcholine transporter
NCBI Official Synonym Full Names
solute carrier family 18 (vesicular acetylcholine transporter), member 3
NCBI Official Symbol
SLC18A3
NCBI Official Synonym Symbols
VACHT
NCBI Protein Information
vesicular acetylcholine transporter
UniProt Protein Name
Vesicular acetylcholine transporter
UniProt Gene Name
SLC18A3
UniProt Synonym Gene Names
VACHT; VAChT
UniProt Entry Name
VACHT_HUMAN

NCBI Description

This gene is a member of the vesicular amine transporter family. The encoded transmembrane protein transports acetylcholine into secretory vesicles for release into the extracellular space. Acetylcholine transport utilizes a proton gradient established by a vacuolar ATPase. This gene is located within the first intron of the choline acetyltransferase gene. [provided by RefSeq, Jul 2008]

Uniprot Description

SLC18A3: Involved in acetylcholine transport into synaptic vesicles. Belongs to the major facilitator superfamily. Vesicular transporter family.

Protein type: Transporter, SLC family; Transporter; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 10q11.2

Cellular Component: membrane; integral to plasma membrane; plasma membrane

Molecular Function: acetylcholine transmembrane transporter activity

Biological Process: synaptic transmission; acetylcholine transport; neurotransmitter secretion

Research Articles on SLC18A3

Similar Products

Product Notes

The SLC18A3 slc18a3 (Catalog #AAA832831) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Vesicular Acetylcholine Transporter can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:800 - 1:1200. Researchers should empirically determine the suitability of the SLC18A3 slc18a3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Vesicular Acetylcholine Transporter, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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