Rabbit anti-Human VEGFR3 Polyclonal Antibody | anti-FLT4 antibody
Anti-VEGFR3 (Vascular Endothelial Growth Factor Receptor 3, VEGFR-3, Fms-like Tyrosine Kinase 4, FLT-4, Tyrosine-protein Kinase Receptor FLT4, FLT4)
Gene Names
FLT4; PCL; FLT41; LMPH1A; VEGFR3
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Affinity Purified
Synonyms
VEGFR3; Polyclonal Antibody; Anti-VEGFR3 (Vascular Endothelial Growth Factor Receptor 3; VEGFR-3; Fms-like Tyrosine Kinase 4; FLT-4; Tyrosine-protein Kinase Receptor FLT4; FLT4); Vascular Endothelial Growth Factor Receptor 3; FLT4; anti-FLT4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG1
Specificity
Recognizes human FLT4.
Purity/Purification
Affinity Purified
Form/Format
Supplied as a liquid in PBS, 0.1% BSA.
Concentration
~1mg/ml (varies by lot)
Applicable Applications for anti-FLT4 antibody
ELISA; Western Blot; Immunohistochemistry
Application Notes
Suitable for use in Western Blot, ELISA, and Immunohistochemistry.
Recommended Dilutions: Western Blot: 1-10ug/ml (Chemiluminescence)
ELISA: 1:10,000-1:100,000; 50-100ng of control peptide/well
Immunohistochemistry: 2-20ug/ml
Recommended Dilutions: Western Blot: 1-10ug/ml (Chemiluminescence)
ELISA: 1:10,000-1:100,000; 50-100ng of control peptide/well
Immunohistochemistry: 2-20ug/ml
Immunogen
Synthetic peptide corresponding to 20aa of human FLT4, C-terminal, Cytoplasmic domain (KLH).
Source Information
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Temperature: Blue Ice
Shipping Temperature: Blue Ice
Related Product Information for anti-FLT4 antibody
Embryonic vascular system undergoes a series of complex, highly regulated series of events involving differentiation, migration and association of primitive endothelial cells. This process is termed vasculogenesis. A further remodeling of the primitive vascular system forms the mature cardiovascular system. This process is known as angiogenesis (sprouting of new capillary vessels from pre-existing vasculature). Study of tumor angiogenesis has led to the identification of several proteins including basic fibroblast growth factor (bFGF) and vascular endothelial growth factor. VEGF acts by interacting with a family of largely endothelial-specific receptor tyrosine kinases that includes VEGFR-1 (flt-1/flk-2), VEGFR-2 (flk- 1/KDR), and VEGFR-3/Flt-4. Disruption of VEGFRs interferes with differentiation of endothelial cells and it is lethal for the embryo. FLT-4 (mouse 1363aa and human 1298aa), a receptor protein tyrosine kinase, is a receptor for VEGF-C. Mouse FLT-4 protein topology: 1-24aa signal peptide, 25-1363 mature protein (25-775 EC domain, 776-797aa TM domain, 798-1363aa CP domain). FLT-4 is type 1 membrane protein. It is expressed in adult lung, and liver, and in fetal liver, brain, intestine, and placenta.
Product Categories/Family for anti-FLT4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
145,599 Da
NCBI Official Full Name
vascular endothelial growth factor receptor 3 isoform 1
NCBI Official Synonym Full Names
fms-related tyrosine kinase 4
NCBI Official Symbol
FLT4
NCBI Official Synonym Symbols
PCL; FLT41; LMPH1A; VEGFR3
NCBI Protein Information
vascular endothelial growth factor receptor 3; FLT-4; VEGFR-3; OTTHUMP00000161539; OTTHUMP00000223511; OTTHUMP00000223512; soluble VEGFR3 variant 1; soluble VEGFR3 variant 2; soluble VEGFR3 variant 3; fms-like tyrosine kinase 4; tyrosine-protein kinase receptor FLT4
UniProt Protein Name
Vascular endothelial growth factor receptor 3
Protein Family
UniProt Gene Name
FLT4
UniProt Entry Name
VGFR3_HUMAN
Similar Products
Product Notes
The FLT4 flt4 (Catalog #AAA623912) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-VEGFR3 (Vascular Endothelial Growth Factor Receptor 3, VEGFR-3, Fms-like Tyrosine Kinase 4, FLT-4, Tyrosine-protein Kinase Receptor FLT4, FLT4) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's VEGFR3 can be used in a range of immunoassay formats including, but not limited to, ELISA; Western Blot; Immunohistochemistry. Suitable for use in Western Blot, ELISA, and Immunohistochemistry. Recommended Dilutions: Western Blot: 1-10ug/ml (Chemiluminescence) ELISA: 1:10,000-1:100,000; 50-100ng of control peptide/well Immunohistochemistry: 2-20ug/ml. Researchers should empirically determine the suitability of the FLT4 flt4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VEGFR3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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