Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Mouse Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Polyclonal Antibody | anti-VEGFR2 antibody
Polyclonal Antibody to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2)
MGHHHHHHSGSEF- NTTLQ ITCRGQRDLD WLWPNAQRDS EERVLVTECG GGDSIFCKTL TIPRVVGNDT GAYKCSYRDV DIASTVYVYV RDYRSPFIAS VSDQHGIVYI TENKNKTVVI PCRGSISNLN VSLCARYPEK RFVPDGNRIS WDSEIGFTLP SYMISYAGMV FCEAKINDET YQSIMYIVVV VGYRIYDVIL SPPHEIELSA GEKLVLNCTA RTELNVGLDF TWHSPPSKSH HKKIVNRDVK PFPGTVAKMF LSTLTIESVT KSDQGEYTCV ASSGRMIKRN RT
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:MouseTissue))
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:MouseTissue))
NCBI and Uniprot Product Information
Uniprot Description
VEGFR2: a receptor tyrosine kinase of the VEGFR family. High affinity receptor for VEGF and VEGF-C. Ligand binding induces autophosphorylation and activation. Activated receptor recruits proteins including Shc, GRB2, PI3K, Nck, SHP-1 and SHP-2. Plays a key role in vascular development and regulation of vascular permeability.
Protein type: EC 2.7.10.1; Kinase, protein; Membrane protein, integral; Protein kinase, TK; Protein kinase, tyrosine (receptor); TK group; VEGFR family
Chromosomal Location of Human Ortholog: 5 C3.3|5 40.23 cM
Cellular Component: cell junction; cell periphery; cell soma; cell surface; cytoplasm; cytoplasmic vesicle; early endosome; endoplasmic reticulum; endosome; external side of plasma membrane; extracellular region; Golgi apparatus; integral component of membrane; integral component of plasma membrane; membrane; membrane raft; neuron projection; nucleus; plasma membrane
Molecular Function: ATP binding; growth factor binding; identical protein binding; integrin binding; kinase activity; nucleotide binding; protein binding; protein kinase activity; protein tyrosine kinase activity; transferase activity; transmembrane receptor protein tyrosine kinase activity; vascular endothelial growth factor binding; vascular endothelial growth factor-activated receptor activity
Biological Process: alveolus development; angiogenesis; branching morphogenesis of a tube; calcium ion homeostasis; cell differentiation; cell fate commitment; cell maturation; cell migration; cell migration during sprouting angiogenesis; cellular response to hydrogen sulfide; elevation of cytosolic calcium ion concentration; embryonic hemopoiesis; endocardium development; endochondral bone growth; endothelial cell differentiation; endothelium development; ERK1 and ERK2 cascade; hemopoiesis; lung development; lymph vessel development; male gonad development; multicellular organism development; negative regulation of apoptosis; negative regulation of endothelial cell apoptotic process; negative regulation of gene expression; negative regulation of neuron apoptosis; neuron projection morphogenesis; ovarian follicle development; peptidyl-tyrosine autophosphorylation; peptidyl-tyrosine phosphorylation; phosphorylation; positive regulation of angiogenesis; positive regulation of blood vessel diameter; positive regulation of blood vessel endothelial cell migration; positive regulation of BMP signaling pathway; positive regulation of calcium-mediated signaling; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway; positive regulation of endothelial cell migration; positive regulation of endothelial cell proliferation; positive regulation of epithelial cell proliferation; positive regulation of ERK1 and ERK2 cascade; positive regulation of focal adhesion assembly; positive regulation of long-term neuronal synaptic plasticity; positive regulation of macroautophagy; positive regulation of MAPK cascade; positive regulation of mesenchymal cell proliferation; positive regulation of mitochondrial depolarization; positive regulation of mitochondrial fission; positive regulation of nitric-oxide synthase biosynthetic process; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of positive chemotaxis; positive regulation of protein phosphorylation; positive regulation of TOR signaling pathway; positive regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of vasculogenesis; post-embryonic camera-type eye morphogenesis; protein amino acid phosphorylation; protein autophosphorylation; protein kinase B signaling; regulation of cell shape; regulation of endothelial cell differentiation; regulation of endothelial cell proliferation; regulation of hematopoietic progenitor cell differentiation; response to drug; response to hypoxia; surfactant homeostasis; transmembrane receptor protein tyrosine kinase signaling pathway; vascular endothelial growth factor receptor signaling pathway; vasculogenesis
Research Articles on VEGFR2
Similar Products
Product Notes
The VEGFR2 kdr (Catalog #AAA2005053) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the VEGFR2 kdr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF- NTTLQ ITCRGQRDLD WLWPNAQRDS EERVLVTECG GGDSIFCKTL TIPRVVGNDT GAYKCSYRDV DIASTVYVYV RDYRSPFIAS VSDQHGIVYI TENKNKTVVI PCRGSISNLN VSLCARYPEK RFVPDGNRIS WDSEIGFTLP SYMISYAGMV FCEAKINDET YQSIMYIVVV VGYRIYDVIL SPPHEIELSA GEKLVLNCTA RTELNVGLDF TWHSPPSKSH HKKIVNRDVK PFPGTVAKMF LSTLTIESVT KSDQGEYTCV ASSGRMIKRN RT. It is sometimes possible for the material contained within the vial of "Vascular Endothelial Growth Factor Receptor 2 (VEGFR2), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
