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Western Blot (WB) (Western blot analysis of VAMP4 in lysates of K562 , using VAMP4 Antibody(MBS9603183).)

Rabbit anti-Human, Mouse VAMP4 Polyclonal Antibody | anti-VAMP4 antibody

VAMP4 Antibody

Gene Names
VAMP4; VAMP-4; VAMP24
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
VAMP4; Polyclonal Antibody; VAMP4 Antibody; VAMP 24; VAMP 4; VAMP-4; VAMP24; VAMP4 protein; VAMP4_HUMAN; Vesicle associated membrane protein 4; Vesicle associated membrane protein 4 isoform CRA a; Vesicle associated membrane protein 4 isoform CRA b; Vesicle-associated membrane protein 4; anti-VAMP4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
VAMP4 antibody detects endogenous levels of VAMP4
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
140
Applicable Applications for anti-VAMP4 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide derived from human VAMP4
Subcellular Location
Golgi Apparatus
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of VAMP4 in lysates of K562 , using VAMP4 Antibody(MBS9603183).)

Western Blot (WB) (Western blot analysis of VAMP4 in lysates of K562 , using VAMP4 Antibody(MBS9603183).)
Related Product Information for anti-VAMP4 antibody
Function: Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule.
Subunit Structure: Identified in a complex containing STX6, STX12, VAMP4 and VTI1A (By similarity). Interacts with BAIAP3; this interaction is increased in the presence of calcium (PubMed:28626000).
Similarity: Belongs to the synaptobrevin family.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 16 kD
Predicted: 17 kDa
NCBI Official Full Name
vesicle-associated membrane protein 4 isoform 2
NCBI Official Synonym Full Names
vesicle associated membrane protein 4
NCBI Official Symbol
VAMP4
NCBI Official Synonym Symbols
VAMP-4; VAMP24
NCBI Protein Information
vesicle-associated membrane protein 4
UniProt Protein Name
Vesicle-associated membrane protein 4
UniProt Gene Name
VAMP4
UniProt Synonym Gene Names
VAMP-4

NCBI Description

Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport. [provided by RefSeq, Jul 2008]

Uniprot Description

Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule.

Research Articles on VAMP4

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Product Notes

The VAMP4 vamp4 (Catalog #AAA9603183) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The VAMP4 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's VAMP4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the VAMP4 vamp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VAMP4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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