Immunohistochemistry (IHC)-Paraffin
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7126684(VAMP4 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200))
Rabbit anti-Human, Mouse VAMP4 Polyclonal Antibody | anti-VAMP4 antibody
VAMP4 Antibody
WB: 1:500-1:2000
IHC: 1:25-1:100
Immunohistochemistry (IHC)-Paraffin
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7126684(VAMP4 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200))
Immunohistochemistry (IHC)-Paraffin
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7126684(VAMP4 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200))
SDS-Page
(Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane 1-4: PC3, TM4, hela and K562 cell, Primary antibody: MBS7126684(VAMP4 Antibody) at dilution 1/650 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds)
SDS-Page
(Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane 1-4: PC3, TM4, hela and K562 cell, Primary antibody: MBS7126684(VAMP4 Antibody) at dilution 1/650 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds)
NCBI and Uniprot Product Information
NCBI Description
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport. [provided by RefSeq, Jul 2008]
Uniprot Description
VAMP4: Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule. Belongs to the synaptobrevin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1q24-q25
Cellular Component: SNARE complex; Golgi membrane; Golgi apparatus; cell surface; lysosome; integral to membrane; trans-Golgi network; endosome
Molecular Function: SNAP receptor activity; SNARE binding
Biological Process: regulation of Golgi to plasma membrane protein transport; ER to Golgi vesicle-mediated transport; exocytosis; Golgi to plasma membrane protein transport; microtubule cytoskeleton organization and biogenesis
Research Articles on VAMP4
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Product Notes
The VAMP4 vamp4 (Catalog #AAA7126684) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The VAMP4 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's VAMP4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:2000-1:5000 WB: 1:500-1:2000 IHC: 1:25-1:100. Researchers should empirically determine the suitability of the VAMP4 vamp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VAMP4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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