Western Blot (WB)
(VAMP3 Antibody (Center) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the VAMP3 antibody detected the VAMP3 protein (arrow).)
Rabbit VAMP3 Polyclonal Antibody | anti-VAMP3 antibody
VAMP3 Antibody (Center)
Western Blot (WB)
(VAMP3 Antibody (Center) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the VAMP3 antibody detected the VAMP3 protein (arrow).)
Western Blot (WB)
(VAMP3 Antibody (Center) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the VAMP3 antibody detected the VAMP3 protein (arrow).)
Western Blot (WB)
(VAMP3 Antibody (Center) western blot analysis in zebra fish brain tissue lysates (35ug/lane).This demonstrates the VAMP3 antibody detected the VAMP3 protein (arrow).)
Western Blot (WB)
(VAMP3 Antibody (Center) western blot analysis in zebra fish brain tissue lysates (35ug/lane).This demonstrates the VAMP3 antibody detected the VAMP3 protein (arrow).)
Immunohistochemistry (IHC)
(VAMP3 Antibody (Center) (MBS9204928)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of VAMP3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(VAMP3 Antibody (Center) (MBS9204928)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of VAMP3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
synaptosomal-associated protein are the main components of a
protein complex involved in the docking and/or fusion of synaptic
vesicles with the presynaptic membrane. This gene is a member of
the vesicle-associated membrane protein (VAMP)/synaptobrevin
family. Because of its high homology to other known VAMPs, its
broad tissue distribution, and its subcellular localization, the
protein encoded by this gene was shown to be the human equivalent
of the rodent cellubrevin. In platelets the protein resides on a
compartment that is not mobilized to the plasma membrane on calcium
or thrombin stimulation.
Fader, C.M., et al. Biochim. Biophys. Acta 1793(12):1901-1916(2009)
Kean, M.J., et al. J. Cell. Sci. 122 (PT 22), 4089-4098 (2009) :
Vassilopoulos, S., et al. Science 324(5931):1192-1196(2009)
Luftman, K., et al. Biochem. Biophys. Res. Commun. 380(1):65-70(2009)
NCBI and Uniprot Product Information
NCBI Description
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. [provided by RefSeq, Jul 2008]
Uniprot Description
VAMP3: SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network. Belongs to the synaptobrevin family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p36.23
Cellular Component: neuron projection; cell surface; clathrin-coated vesicle; intracellular membrane-bound organelle; integral to membrane; clathrin coated vesicle membrane; cytosol; secretory granule; SNARE complex; recycling endosome; synaptic vesicle; apical plasma membrane; plasma membrane; intracellular; cell junction
Molecular Function: SNAP receptor activity; protein binding; SNARE binding; syntaxin-1 binding
Biological Process: vesicle-mediated transport; vesicle fusion; exocytosis; neurotransmitter secretion; Golgi to plasma membrane protein transport; protein complex assembly; positive regulation of immunoglobulin secretion; retrograde transport, endosome to Golgi; positive regulation of receptor recycling; vesicle docking during exocytosis; calcium ion-dependent exocytosis
Research Articles on VAMP3
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Product Notes
The VAMP3 vamp3 (Catalog #AAA9204928) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 15-43. The VAMP3 Antibody (Center) reacts with Human, Mouse, Zebrafish (Predicted Reactivity: Bovine, Rat, Monkey) and may cross-react with other species as described in the data sheet. AAA Biotech's VAMP3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P). WB~~1:1000!!IHC-P~~1:10~50. Researchers should empirically determine the suitability of the VAMP3 vamp3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VAMP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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