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Western Blot

Rabbit anti-Human UV excision repair protein RAD23 homolog A Polyclonal Antibody | anti-RAD23 antibody

Rabbit anti- human UV excision repair protein RAD23 homolog A polyclonal Antibody, HRP conjugated

Gene Names
RAD23A; HR23A; HHR23A
Reactivity
Human
Applications
ELISA
Purity
Caprylic Acid Ammonium Sulfate Precipitation Purified
Synonyms
UV excision repair protein RAD23 homolog A; Polyclonal Antibody; Rabbit anti- human UV excision repair protein RAD23 homolog A polyclonal Antibody; HRP conjugated; HR23A hHR23A; anti-RAD23 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Sequence Length
362
Applicable Applications for anti-RAD23 antibody
ELISA (EIA)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
HRP
Immunogen
Recombinant human UV excision repair protein RAD23 homolog A protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-47348 / sc-47349 / sc-49037 / sc-49039 / sc-67162
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot

Western Blot

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39,538 Da
NCBI Official Full Name
UV excision repair protein RAD23 homolog A isoform 2
NCBI Official Synonym Full Names
RAD23 homolog A, nucleotide excision repair protein
NCBI Official Symbol
RAD23A
NCBI Official Synonym Symbols
HR23A; HHR23A
NCBI Protein Information
UV excision repair protein RAD23 homolog A
UniProt Protein Name
UV excision repair protein RAD23 homolog A
UniProt Gene Name
RAD23A
UniProt Synonym Gene Names
HR23A; hHR23A
UniProt Entry Name
RD23A_HUMAN

NCBI Description

The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair. Proteins in this family have a modular domain structure consisting of an ubiquitin-like domain (UbL), ubiquitin-associated domain 1 (UbA1), XPC-binding domain and UbA2. The protein encoded by this gene plays an important role in nucleotide excision repair and also in delivery of polyubiquitinated proteins to the proteasome. Alternative splicing results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Jun 2012]

Uniprot Description

RAD23A: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. Belongs to the RAD23 family.

Protein type: DNA-binding; DNA repair, damage

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: nucleus; proteasome complex

Molecular Function: damaged DNA binding; polyubiquitin binding; protein binding; single-stranded DNA binding

Biological Process: nucleotide-excision repair; positive regulation of viral genome replication; proteasomal ubiquitin-dependent protein catabolic process; regulation of proteasomal ubiquitin-dependent protein catabolic process; viral reproduction

Research Articles on RAD23

Similar Products

Product Notes

The RAD23 rad23a (Catalog #AAA715501) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti- human UV excision repair protein RAD23 homolog A polyclonal Antibody, HRP conjugated reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's UV excision repair protein RAD23 homolog A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the RAD23 rad23a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UV excision repair protein RAD23 homolog A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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