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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human small intestine tissue using MBS7053109 at dilution of 1:100)

Rabbit anti-Human USP6NL Polyclonal Antibody | anti-USP6NL antibody

USP6NL Antibody

Gene Names
USP6NL; RNTRE; TRE2NL; USP6NL-IT1
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
>95%, Protein G purified
Synonyms
USP6NL; Polyclonal Antibody; USP6NL Antibody; USP6 N-terminal-like protein; Related to the N-terminus of tre; RN-tre; KIAA0019; anti-USP6NL antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
845
Applicable Applications for anti-USP6NL antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:20-1:200
Immunogen
Recombinant Human USP6 N-terminal-like protein (387-693AA)
Conjugation
Non-conjugated
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human small intestine tissue using MBS7053109 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human small intestine tissue using MBS7053109 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human adrenal gland tissue using MBS7053109 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human adrenal gland tissue using MBS7053109 at dilution of 1:100)
Related Product Information for anti-USP6NL antibody
Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
95,997 Da
NCBI Official Full Name
USP6 N-terminal-like protein isoform 2
NCBI Official Synonym Full Names
USP6 N-terminal like
NCBI Official Symbol
USP6NL
NCBI Official Synonym Symbols
RNTRE; TRE2NL; USP6NL-IT1
NCBI Protein Information
USP6 N-terminal-like protein
UniProt Protein Name
USP6 N-terminal-like protein
UniProt Gene Name
USP6NL
UniProt Synonym Gene Names
KIAA0019; RN-tre

Uniprot Description

USP6NL: a widely-expressed GTPase activating protein (GAP) for RAB5A. Involved in endosomal trafficking, and localizes to the centrosome. In complex with Eps8 inhibits internalization of EGFR.

Protein type: GAPs; GAPs, Rab; Ubiquitin-specific protease

Chromosomal Location of Human Ortholog: 10p14

Cellular Component: cytoplasmic vesicle; cytosol; endomembrane system; plasma membrane; trans-Golgi network membrane

Molecular Function: GTPase activator activity; Rab GTPase binding

Biological Process: Golgi organization and biogenesis; intracellular protein transport; plasma membrane to endosome transport; regulation of vesicle fusion; virus assembly

Research Articles on USP6NL

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Product Notes

The USP6NL usp6nl (Catalog #AAA7053109) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The USP6NL Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's USP6NL can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:20-1:200. Researchers should empirically determine the suitability of the USP6NL usp6nl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "USP6NL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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