Western Blot (WB)
(Western blot analysis of USP48 expression in Hela cell lysate, The lane on the left is treated with the antigen-specific peptide.)
Rabbit USP48 Polyclonal Antibody | anti-USP48 antibody
USP48 Antibody
Gene Names
USP48; USP31; RAP1GA1
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
USP48; Polyclonal Antibody; USP48 Antibody; AAH67261; Deubiquitinating enzyme 48; DKFZp762M1713; EC 3.1.2.15; Kiaa4202; MGC132556; MGC14879; RAP1GA1; Synaptic ubiquitin specific protease; synUSP; Ubiquitin carboxyl terminal hydrolase 48; Ubiquitin carboxyl-terminal hydrolase 48; Ubiquitin specific peptidase 48; Ubiquitin specific processing protease 48; Ubiquitin specific protease 31; Ubiquitin specific protease 48; Ubiquitin thioesterase 48; Ubiquitin thiolesterase 48; Ubiquitin-specific-processing protease 48; UBP48_HUMAN; USP31; anti-USP48 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
USP48 antibody detects endogenous levels of total USP48
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
485
Applicable Applications for anti-USP48 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthesized peptide
Subcellular Location
Cytoplasm. Nucleus.
Tissue Specificity
Widely expressed.
Predicted Cross Reactivity
Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Similarity
Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (92%), Dog (100%), Chicken (92%), Xenopus (82%)
Conjugation
Unconjugated
Western Blot (WB)
(Western blot analysis of USP48 expression in Hela cell lysate, The lane on the left is treated with the antigen-specific peptide.)
Western Blot (WB)
(Western blot analysis of USP48 expression in Hela cell lysate, The lane on the left is treated with the antigen-specific peptide.)
Related Product Information for anti-USP48 antibody
Function: Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites.
Subunit Structure: Interacts with TRAF2 and RELA.
Similarity: Belongs to the peptidase C19 family.
Subunit Structure: Interacts with TRAF2 and RELA.
Similarity: Belongs to the peptidase C19 family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 145 kDa
Predicted: 120 kDa
Predicted: 120 kDa
NCBI Official Full Name
ubiquitin carboxyl-terminal hydrolase 48 isoform b
NCBI Official Synonym Full Names
ubiquitin specific peptidase 48
NCBI Official Symbol
USP48
NCBI Official Synonym Symbols
USP31; RAP1GA1
NCBI Protein Information
ubiquitin carboxyl-terminal hydrolase 48
UniProt Protein Name
Ubiquitin carboxyl-terminal hydrolase 48
Protein Family
UniProt Gene Name
USP48
UniProt Synonym Gene Names
USP31
NCBI Description
This gene encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Uniprot Description
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites.
Research Articles on USP48
Similar Products
Product Notes
The USP48 usp48 (Catalog #AAA9603796) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The USP48 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's USP48 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the USP48 usp48 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "USP48, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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