Rabbit anti-Human USP24 Polyclonal Antibody | anti-USP24 antibody

USP24 Antibody

Cat. Num. AAA7107679

• Reactivity: Human
• Applications: ELISA, Immunohistochemistry
• Purity: >95%, Protein G purified
• Synonyms: USP24; Polyclonal Antibody; USP24 Antibody; Ubiquitin carboxyl-terminal hydrolase 24; Deubiquitinating enzyme 24; Ubiquitin thioesterase 24; Ubiquitin-specific-processing protease 24; KIAA1057; anti-USP24 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 2620

• Applicable Applications for anti-USP24 antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Application Notes: IHC: 1:200-1:500
• Immunogen: Recombinant Human Ubiquitin carboxyl-terminal hydrolase 24 protein (2509-2620AA)
• Conjugation: Non-conjugated
• Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(IHC image of MBS7107679 diluted at 1:200 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 degree C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.)

Immunohistochemistry (IHC)

(IHC image of MBS7107679 diluted at 1:200 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 degree C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.)

Related Product Information for anti-USP24 antibody

Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Deubiquitinates DDB2, preventing its proteasomal degradation.

Product Categories/Family for anti-USP24 antibody

Epigenetics and Nuclear Signaling; Cell Biology

NCBI and Uniprot Product Information

• NCBI GI #: 260064009
• NCBI GeneID: 23358
• NCBI Accession #: NP_056121.2
• NCBI GenBank Nucleotide #: NM_015306.2
• UniProt Accession #: Q9UPU5; Q6ZSY2; Q8N2Y4; Q9NXD1
• Molecular Weight: 294,365 Da
• NCBI Official Full Name: ubiquitin carboxyl-terminal hydrolase 24
• NCBI Official Synonym Full Names: ubiquitin specific peptidase 24
• NCBI Official Symbol: USP24
• NCBI Protein Information: ubiquitin carboxyl-terminal hydrolase 24
• UniProt Protein Name: Ubiquitin carboxyl-terminal hydrolase 24
• UniProt Gene Name: USP24
• UniProt Synonym Gene Names: KIAA1057

NCBI Description

Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008]

Uniprot Description

Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Deubiquitinates DDB2, preventing its proteasomal degradation.