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Western Blot (WB) (Western Blot: Sample: Recombinant protein.)

Rabbit anti-Human Urotensin 2 (UST2) Polyclonal Antibody | anti-UST2 antibody

Polyclonal Antibody to Urotensin 2 (UST2)

Gene Names
UTS2; UII; U-II; UCN2; PRO1068
Reactivity
Human
Applications
Immunocytochemistry, Immunohistochemistry, ELISA, Western Blot
Purity
Affinity Chromatography
Synonyms
Urotensin 2 (UST2); Polyclonal Antibody; Polyclonal Antibody to Urotensin 2 (UST2); anti-UST2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against UST2. It has been selected for its ability to recognize UST2 in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
Concentration
500ug/mL (varies by lot)
Sequence
Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below.
MGHHHHHHSG SEF- S LPLLDSREIS FQLSAPHEDA RLTPEELERA SLLQILPEML GAERGDILRK ADSSTNIFNP RGNLRKFQDF SGQDPNILLS HLLARIWKPY KKRETPDCFW
Sequence Length
124
Applicable Applications for anti-UST2 antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)
Application Notes
Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Immunogen
Recombinant UST2 (Ser20~Trp120) expressed in E.coli.
Cross Reactivity
Human
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2041360
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Western Blot (WB)

(Western Blot: Sample: Recombinant protein.)

Western Blot (WB) (Western Blot: Sample: Recombinant protein.)

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Human Glioma Tissue))

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Human Glioma Tissue))

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16,029 Da
NCBI Official Full Name
urotensin-2 isoform b preproprotein
NCBI Official Synonym Full Names
urotensin 2
NCBI Official Symbol
UTS2
NCBI Official Synonym Symbols
UII; U-II; UCN2; PRO1068
NCBI Protein Information
urotensin-2
UniProt Protein Name
Urotensin-2
UniProt Gene Name
UTS2
UniProt Synonym Gene Names
U-II; UII

NCBI Description

This gene encodes a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide. Transcript variants encoding different preproprotein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

UTS2: Highly potent vasoconstrictor. Belongs to the urotensin-2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1p36.23

Cellular Component: cell; extracellular region; extracellular space

Molecular Function: hormone activity; receptor binding

Biological Process: elevation of cytosolic calcium ion concentration; muscle contraction; negative regulation of blood pressure; negative regulation of glomerular filtration; negative regulation of heart rate; negative regulation of insulin secretion; positive regulation of angiogenesis; positive regulation of blood pressure; positive regulation of cell differentiation; positive regulation of circadian sleep/wake cycle, REM sleep; positive regulation of collagen biosynthetic process; positive regulation of fibroblast proliferation; positive regulation of heart rate; positive regulation of synaptic transmission, cholinergic; regulation of blood pressure; response to drug; response to hypoxia; response to testosterone stimulus; synaptic transmission

Research Articles on UST2

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Product Notes

The UST2 uts2 (Catalog #AAA2005385) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Urotensin 2 (UST2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Urotensin 2 (UST2) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the UST2 uts2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF- S LPLLDSREIS FQLSAPHEDA RLTPEELERA SLLQILPEML GAERGDILRK ADSSTNIFNP RGNLRKFQDF SGQDPNILLS HLLARIWKPY KKRETPDCFW. It is sometimes possible for the material contained within the vial of "Urotensin 2 (UST2), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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