Rabbit anti-Rat Uncoupling Protein 2, Mitochondrial (UCP2) Polyclonal Antibody | anti-UCP2 antibody
Polyclonal Antibody to Uncoupling Protein 2, Mitochondrial (UCP2)
MGHHHHHHSGSEF-LY DSVKQFYTKG SEHAGIGSRL LAGSTTGALA VAVAQPTDVV KVRFQAQARA GGGRRYQSTV EAYKTIAREE GIRGLWKGTS PNVARNAIVN CTELVTYDLI KDTLLKANLM TDDLPC
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
NCBI and Uniprot Product Information
NCBI Description
catalyzes a proton leak across the inner mitochondrial membrane to uncouple oxidative phosphorylation; may reduce the concentration of reactive ozygen species in mitochondria [RGD, Feb 2006]
Uniprot Description
UCP2: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat. Belongs to the mitochondrial carrier family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial; Transporter
Chromosomal Location of Human Ortholog: 1q32
Cellular Component: cytoplasm; integral component of membrane; mitochondrial inner membrane; mitochondrion
Molecular Function: oxidative phosphorylation uncoupler activity
Biological Process: aging; cellular response to amino acid starvation; cellular response to hormone stimulus; cellular response to insulin stimulus; female pregnancy; mitochondrial transport; negative regulation of apoptosis; proton transport; regulation of mitochondrial membrane potential; response to cold; response to glucose stimulus; response to hypoxia; response to superoxide
Research Articles on UCP2
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Product Notes
The UCP2 ucp2 (Catalog #AAA2005909) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Uncoupling Protein 2, Mitochondrial (UCP2) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Uncoupling Protein 2, Mitochondrial (UCP2) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the UCP2 ucp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG SEF-LY DSVKQFYTKG SEHAGIGSRL LAGSTTGALA VAVAQPTDVV KVRFQAQARA GGGRRYQSTV EAYKTIAREE GIRGLWKGTS PNVARNAIVN CTELVTYDLI KDTLLKANLM TDDLPC. It is sometimes possible for the material contained within the vial of "Uncoupling Protein 2, Mitochondrial (UCP2), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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