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Western Blot (WB) (0.3ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

Goat UNC5CL Polyclonal Antibody | anti-UNC5CL antibody

Goat anti-UNC5CL Antibody

Gene Names
UNC5CL; ZUD; MUXA
Reactivity
Tested: Human; Expected from sequence similarity: Human
Applications
ELISA, Western Blot
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
UNC5CL; Polyclonal Antibody; Goat anti-UNC5CL Antibody; unc-5 homolog C (C. elegans)-like; MGC34763; ZUD; OTTHUMP00000016362; ZU5 and death domain containing; ZU5 and death domain-containing protein; unc-5 homolog C-like; UNC5CL antibody; unc-5 homolog C (C. elegans)-like antibody; MGC34763 antibody; ZUD antibody; OTTHUMP00000016362 antibody; ZU5 and death domain containing antibody; ZU5 and death domain-containing protein antibody; unc-5 homolog C-like antibody; anti-UNC5CL antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Tested: Human; Expected from sequence similarity: Human
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
KHCAEQPSHARTY
Sequence Length
518
Applicable Applications for anti-UNC5CL antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 8000.
Western Blot: Approx.55kDa band observed in Human Kidney and Ovary lysates (calculated MW of 57.7kDa according to NP_775832.1). Recommended concentration: 0.3-1ug/ml.
Immunogen
Peptide with sequence KHCAEQPSHARTY, from the internal region of the protein sequence according to NP_775832.1.
Epitope
Internal region
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

Western Blot (WB)

(0.3ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

Western Blot (WB) (0.3ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
57,818 Da
NCBI Official Full Name
UNC5C-like protein
NCBI Official Synonym Full Names
unc-5 family C-terminal like
NCBI Official Symbol
UNC5CL
NCBI Official Synonym Symbols
ZUD; MUXA
NCBI Protein Information
UNC5C-like protein
UniProt Protein Name
UNC5C-like protein
Protein Family
UniProt Gene Name
UNC5CL
UniProt Synonym Gene Names
ZUD
UniProt Entry Name
UN5CL_HUMAN

Uniprot Description

UNC5CL: Inhibits NF-kappa-B-dependent transcription by impairing NF-kappa-B binding to its targets. Belongs to the unc-5 family.

Protein type: Membrane protein, integral; Inhibitor

Chromosomal Location of Human Ortholog: 6p21.1

Cellular Component: cytoplasm; integral to membrane; membrane

Molecular Function: peptidase activity

Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of JNK cascade; proteolysis; signal transduction

Research Articles on UNC5CL

Similar Products

Product Notes

The UNC5CL unc5cl (Catalog #AAA422122) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-UNC5CL Antibody reacts with Tested: Human; Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's UNC5CL can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 8000. Western Blot: Approx.55kDa band observed in Human Kidney and Ovary lysates (calculated MW of 57.7kDa according to NP_775832.1). Recommended concentration: 0.3-1ug/ml. Researchers should empirically determine the suitability of the UNC5CL unc5cl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: KHCAEQPSHA RTY. It is sometimes possible for the material contained within the vial of "UNC5CL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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