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Western Blot (WB) (UGT2B7 Antibody (N-term) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the UGT2B7 antibody detected the UGT2B7 protein (arrow).)

Rabbit anti-Human UGT2B7 Polyclonal Antibody | anti-UGT2B7 antibody

UGT2B7, NT (UGT2B7, UGTB2B9, UDP-glucuronosyltransferase 2B7, 3,4-catechol estrogen-specific UDPGT, UDP-glucuronosyltransferase 2B9, UDPGTh-2) (PE)

Gene Names
UGT2B7; UGT2B9; UDPGTH2; UDPGT2B7; UDPGT 2B9
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
UGT2B7; Polyclonal Antibody; NT (UGT2B7; UGTB2B9; UDP-glucuronosyltransferase 2B7; 3; 4-catechol estrogen-specific UDPGT; UDP-glucuronosyltransferase 2B9; UDPGTh-2) (PE); UDPGTh-2; anti-UGT2B7 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Applicable Applications for anti-UGT2B7 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
UGT2B7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-127 amino acids from the N-terminal region of human UGT2B7.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(UGT2B7 Antibody (N-term) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the UGT2B7 antibody detected the UGT2B7 protein (arrow).)

Western Blot (WB) (UGT2B7 Antibody (N-term) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the UGT2B7 antibody detected the UGT2B7 protein (arrow).)
Related Product Information for anti-UGT2B7 antibody
The UGTs (EC 2.4.1.17) serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT2B7 has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Its subcellular location is the microsome.
Product Categories/Family for anti-UGT2B7 antibody
References
Joy, M.S., et al. Eur. J. Clin. Pharmacol. 66(11):1119-1130(2010). Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884(2010). Hu, M., et al. Pharmacogenet. Genomics 20(10):634-637(2010). Woillard, J.B., et al. Br J Clin Pharmacol 69(6):675-683(2010). Hwang, M.S., et al. Drug Metab. Pharmacokinet. 25(4):398-402(2010).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
60,695 Da
NCBI Official Full Name
UDP-glucuronosyltransferase 2B7
NCBI Official Synonym Full Names
UDP glucuronosyltransferase 2 family, polypeptide B7
NCBI Official Symbol
UGT2B7
NCBI Official Synonym Symbols
UGT2B9; UDPGTH2; UDPGT2B7; UDPGT 2B9
NCBI Protein Information
UDP-glucuronosyltransferase 2B7; UDPGTh-2; UDPGT 2B7; 3,4-catechol estrogen specific; UDP glucuronosyltransferase 2B7; UDP-glucuronosyltransferase 2B9; 3,4-catechol estrogen-specific UDPGT; UDP-glucuronyltransferase, family 2, beta-7
UniProt Protein Name
UDP-glucuronosyltransferase 2B7
UniProt Gene Name
UGT2B7
UniProt Synonym Gene Names
UGTB2B9; UDPGT 2B7; UDPGT 2B9
UniProt Entry Name
UD2B7_HUMAN

NCBI Description

The protein encoded by this gene belongs to the UDP-glycosyltransferase (UGT) family. UGTs serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This protein is localized in the microsome membrane, and has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. [provided by RefSeq, Sep 2011]

Uniprot Description

UGT2B7: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Belongs to the UDP-glycosyltransferase family.

Protein type: Membrane protein, integral; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; Carbohydrate Metabolism - pentose and glucuronate interconversions; Lipid Metabolism - androgen and estrogen; Transferase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Carbohydrate Metabolism - starch and sucrose; Cofactor and Vitamin Metabolism - retinol; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 2.4.1.17; Xenobiotic Metabolism - drug metabolism - other enzymes; Carbohydrate Metabolism - ascorbate and aldarate

Chromosomal Location of Human Ortholog: 4q13

Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; membrane; integral to membrane

Molecular Function: retinoic acid binding; glucuronosyltransferase activity

Biological Process: flavonoid biosynthetic process; androgen metabolic process; lipid metabolic process; cellular response to hormone stimulus

Research Articles on UGT2B7

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Product Notes

The UGT2B7 ugt2b7 (Catalog #AAA6361222) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The UGT2B7, NT (UGT2B7, UGTB2B9, UDP-glucuronosyltransferase 2B7, 3,4-catechol estrogen-specific UDPGT, UDP-glucuronosyltransferase 2B9, UDPGTh-2) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's UGT2B7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the UGT2B7 ugt2b7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UGT2B7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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