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Western Blot (WB) (UGT2B4 Antibody (N-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the UGT2B4 antibody detected the UGT2B4 protein (arrow).)

Rabbit anti-Human UGT2B4 Polyclonal Antibody | anti-UGT2B4 antibody

UGT2B4, NT (UGT2B4, UGT2B11, UDP-glucuronosyltransferase 2B4, HLUG25, Hyodeoxycholic acid-specific UDPGT, UDPGTh-1) (FITC)

Gene Names
UGT2B4; HLUG25; UDPGTH1; UGT2B11; UDPGT2B4
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
UGT2B4; Polyclonal Antibody; NT (UGT2B4; UGT2B11; UDP-glucuronosyltransferase 2B4; HLUG25; Hyodeoxycholic acid-specific UDPGT; UDPGTh-1) (FITC); UDPGTh-1; anti-UGT2B4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Applicable Applications for anti-UGT2B4 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
UGT2B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-96 amino acids from the N-terminal region of human UGT2B4.
Conjugate
FITC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(UGT2B4 Antibody (N-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the UGT2B4 antibody detected the UGT2B4 protein (arrow).)

Western Blot (WB) (UGT2B4 Antibody (N-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the UGT2B4 antibody detected the UGT2B4 protein (arrow).)
Related Product Information for anti-UGT2B4 antibody
UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.
Product Categories/Family for anti-UGT2B4 antibody
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Levesque, E., et al. Pharmacogenet. Genomics 20(3):195-210(2010). Yong, M., et al. Cancer Epidemiol. Biomarkers Prev. 19(2):537-546(2010). Li, J., et al. Breast Cancer Res. 12 (2), R19 (2010): Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
60,513 Da
NCBI Official Full Name
UDP-glucuronosyltransferase 2B4
NCBI Official Synonym Full Names
UDP glucuronosyltransferase 2 family, polypeptide B4
NCBI Official Symbol
UGT2B4
NCBI Official Synonym Symbols
HLUG25; UDPGTH1; UGT2B11; UDPGT2B4
NCBI Protein Information
UDP-glucuronosyltransferase 2B4; UDPGTh-1; UDPGT 2B4; hyodeoxycholic acid; UDP glucuronosyltransferase 2B4; hyodeoxycholic acid-specific UDPGT; UDP-glucuronyltransferase, family 2, beta-4
UniProt Protein Name
UDP-glucuronosyltransferase 2B4
UniProt Gene Name
UGT2B4
UniProt Synonym Gene Names
UGT2B11; UDPGT 2B4
UniProt Entry Name
UD2B4_HUMAN

Uniprot Description

UGT2B4: UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4- nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid. Belongs to the UDP-glycosyltransferase family.

Protein type: Carbohydrate Metabolism - pentose and glucuronate interconversions; Transferase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Cofactor and Vitamin Metabolism - retinol; Carbohydrate Metabolism - ascorbate and aldarate; Membrane protein, integral; Xenobiotic Metabolism - drug metabolism - other enzymes; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; Carbohydrate Metabolism - starch and sucrose; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 2.4.1.17; Lipid Metabolism - androgen and estrogen

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; integral to membrane

Molecular Function: retinoic acid binding; glucuronosyltransferase activity

Biological Process: flavonoid biosynthetic process; metabolic process; xenobiotic metabolic process; estrogen catabolic process; cellular response to hormone stimulus

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Product Notes

The UGT2B4 ugt2b4 (Catalog #AAA6361204) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The UGT2B4, NT (UGT2B4, UGT2B11, UDP-glucuronosyltransferase 2B4, HLUG25, Hyodeoxycholic acid-specific UDPGT, UDPGTh-1) (FITC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's UGT2B4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the UGT2B4 ugt2b4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UGT2B4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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