Western Blot (WB)
(Western blot analysis UGGT1 using COLO205 whole cell lysates)
Rabbit anti-Human UGGT1 Polyclonal Antibody | anti-UGGT1 antibody
UGGT1 Antibody
Gene Names
UGGT1; UGT1; HUGT1; UGCGL1
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
UGGT1; Polyclonal Antibody; UGGT1 Antibody; GT; HUGT1; UDP glucose glycoprotein glucosyltransferase 1; UDP Glucose Glycoprotein Glucosyltransferase; UDP--Glc:glycoprotein glucosyltransferase; UDP-glucose ceramide glucosyltransferase-like 1; UDP-glucose:glycoprotein glucosyltransferase 1; UGCGL1; UGGG1; UGGG1_HUMAN; UGGT; Uggt1; UGT1; UGTR; anti-UGGT1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
UGGT1 antibody detects endogenous levels of total UGGT1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
1555
Applicable Applications for anti-UGGT1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human UGGT1
Subcellular Location
Endoplasmic Reticulum Lumen. Endoplasmic reticulum-Golgi intermediate compartment.
Tissue Specificity
Higher levels in pancreas, skeletal muscle, kidney, and brain. Low levels in lung and heart.
Predicted Cross Reactivity
Pig, Zebrafish, Bovine, Horse, Dog
Similarity
Pig (100%), Zebrafish (82%), Bovine (100%), Horse (91%), Dog (100%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis UGGT1 using COLO205 whole cell lysates)
Western Blot (WB)
(Western blot analysis UGGT1 using COLO205 whole cell lysates)
Related Product Information for anti-UGGT1 antibody
Function: Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
Subunit Structure: Monomer as well as in a tight complex with SELENOF (By similarity). Interacts with METTL23.
Similarity: The N-terminal non-catalytic domain is assumed to mediate recognition of proteins with partial folding defects. Belongs to the glycosyltransferase 8 family.
Subunit Structure: Monomer as well as in a tight complex with SELENOF (By similarity). Interacts with METTL23.
Similarity: The N-terminal non-catalytic domain is assumed to mediate recognition of proteins with partial folding defects. Belongs to the glycosyltransferase 8 family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 177 kDa
Predicted: 178 kDa
Predicted: 178 kDa
NCBI Official Full Name
UDP-glucose:glycoprotein glucosyltransferase 1
NCBI Official Synonym Full Names
UDP-glucose glycoprotein glucosyltransferase 1
NCBI Official Symbol
UGGT1
NCBI Official Synonym Symbols
UGT1; HUGT1; UGCGL1
NCBI Protein Information
UDP-glucose:glycoprotein glucosyltransferase 1
UniProt Protein Name
UDP-glucose:glycoprotein glucosyltransferase 1
Protein Family
UniProt Gene Name
UGGT1
UniProt Synonym Gene Names
; UGT1; hUGT1
NCBI Description
UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.[supplied by OMIM, Oct 2009]
Uniprot Description
Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
Research Articles on UGGT1
Similar Products
Product Notes
The UGGT1 uggt1 (Catalog #AAA9608624) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The UGGT1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's UGGT1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the UGGT1 uggt1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UGGT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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