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Western Blot (WB) (Western blot analysis of rat brain tissue extract, probed with UGGT, pAb.)

Rabbit anti-Mouse, Rat UGGT Polyclonal Antibody | anti-Uggt1 antibody

UGGT polyclonal antibody

Gene Names
Uggt1; UGT1; Uggt; rUGT1; Ugcgl1
Reactivity
Mouse, Rat
Applications
Western Blot
Synonyms
UGGT; Polyclonal Antibody; UGGT polyclonal antibody; anti-Uggt1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Specificity
Recognizes mouse and rat UGGT. Detects a band of ~170kDa by Western blot.
Form/Format
Liquid. Whole rabbit serum.
Sequence Length
1551
Applicable Applications for anti-Uggt1 antibody
Western Blot (WB)
Application Notes
Western Blot (1:100 colorimetric, 1:500 ECL)
Suggested dilutions/conditions may not be available for all applications.
Detects a band of ~170kDa by Western blot.
Immunogen
Synthetic peptide corresponding to a portion of rat UGGT.
Preparation and Storage
Long term storage: -20 degree C
Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of rat brain tissue extract, probed with UGGT, pAb.)

Western Blot (WB) (Western blot analysis of rat brain tissue extract, probed with UGGT, pAb.)
Related Product Information for anti-Uggt1 antibody
UDP-glucose:glycoprotein glucosyltransferase (UGGT) is a 170 kDa lumenal endoplasmic reticulum (ER) resident protein that catalyzes monoglucosylation of high mannose oligosaccharides. UGGT catalyzes the transfer of glucose from UDP-glucose to Man7-9GlcNAc2-moiety of unfolded glycoproteins in a Ca2+ dependent reaction. UGGT binds unfolded glycoprotein via an N-acetylglucosamine unit on the oligosaccharide, and hydrophobic amino acids that are exposed in the denatured conformation.
Product Categories/Family for anti-Uggt1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
176,431 Da
NCBI Official Full Name
UDP-glucose:glycoprotein glucosyltransferase 1
NCBI Official Synonym Full Names
UDP-glucose glycoprotein glucosyltransferase 1
NCBI Official Symbol
Uggt1
NCBI Official Synonym Symbols
UGT1; Uggt; rUGT1; Ugcgl1
NCBI Protein Information
UDP-glucose:glycoprotein glucosyltransferase 1
UniProt Protein Name
UDP-glucose:glycoprotein glucosyltransferase 1
UniProt Gene Name
Uggt1
UniProt Synonym Gene Names
; UGT1; rUGT1
UniProt Entry Name
UGGG1_RAT

NCBI Description

enzyme that catalyzes the addition of a glucose residue from UDP-glucose to an N -linked Man(9)GlcNAc(2)oligosaccharide [RGD, Feb 2006]

Uniprot Description

UGCGL1: Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation. Belongs to the glycosyltransferase 8 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transferase; EC 2.4.1.-

Cellular Component: endoplasmic reticulum; endoplasmic reticulum lumen; ER-Golgi intermediate compartment

Molecular Function: protein binding; UDP-glucose:glycoprotein glucosyltransferase activity; unfolded protein binding

Biological Process: 'de novo' posttranslational protein folding; protein amino acid glycosylation; protein folding

Research Articles on Uggt1

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Product Notes

The Uggt1 uggt1 (Catalog #AAA565311) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The UGGT polyclonal antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's UGGT can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot (1:100 colorimetric, 1:500 ECL) Suggested dilutions/conditions may not be available for all applications. Detects a band of ~170kDa by Western blot. Researchers should empirically determine the suitability of the Uggt1 uggt1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UGGT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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