Western Blot (WB)
(Western blot analysis of UDB17 antibody (Center) in Y79 cell line lysates (35ug/lane). UDB17 (arrow) was detected using the purified Pab.)
Rabbit anti-Human UDB17 Polyclonal Antibody | anti-UGT2B17 antibody
UDB17 Antibody (Center)
IHC~P~~1:10~50
Western Blot (WB)
(Western blot analysis of UDB17 antibody (Center) in Y79 cell line lysates (35ug/lane). UDB17 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of UDB17 antibody (Center) in Y79 cell line lysates (35ug/lane). UDB17 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(UDB17 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded human Prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the UDB17 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(UDB17 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded human Prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the UDB17 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Juul,A., J. Clin. Endocrinol. Metab. 94 (3), 1005-1011 (2009)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the uridine diphosphoglucuronosyltransferase protein family. The encoded enzyme catalyzes the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a diverse array of substrates including steroid hormones and lipid-soluble drugs. This process, known as glucuronidation, is an intermediate step in the metabolism of steroids. Copy number variation in this gene is associated with susceptibility to osteoporosis.[provided by RefSeq, Apr 2010]
Uniprot Description
UGT2B17: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. The major substrates of this isozyme are eugenol > 4-methylumbelliferone > dihydrotestosterone (DHT) > androstane-3-alpha,17-beta-diol (3-alpha-diol) > testosterone > androsterone (ADT). Belongs to the UDP-glycosyltransferase family.
Protein type: Carbohydrate Metabolism - pentose and glucuronate interconversions; Lipid Metabolism - androgen and estrogen; Mitochondrial; Xenobiotic Metabolism - drug metabolism - cytochrome P450; EC 2.4.1.17; Carbohydrate Metabolism - ascorbate and aldarate; Xenobiotic Metabolism - metabolism by cytochrome P450; Membrane protein, integral; Xenobiotic Metabolism - drug metabolism - other enzymes; Carbohydrate Metabolism - starch and sucrose; Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; Transferase; Cofactor and Vitamin Metabolism - retinol
Chromosomal Location of Human Ortholog: 4q13
Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; membrane; integral to membrane
Molecular Function: retinoic acid binding; glucuronosyltransferase activity
Biological Process: steroid metabolic process; flavonoid biosynthetic process; cellular response to hormone stimulus
Disease: Bone Mineral Density Quantitative Trait Locus 12
Research Articles on UGT2B17
Similar Products
Product Notes
The UGT2B17 ugt2b17 (Catalog #AAA9213607) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 119-147. The UDB17 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's UDB17 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P). WB~~1:1000 IHC~P~~1:10~50. Researchers should empirically determine the suitability of the UGT2B17 ugt2b17 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UDB17, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
