Western Blot (WB)
(UBE2Z Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the UBE2Z antibody detected the UBE2Z protein (arrow).)
Rabbit UBE2Z Polyclonal Antibody | anti-UBE2Z antibody
UBE2Z Antibody (C-term)
Gene Names
UBE2Z; USE1; HOYS7
Reactivity
Human (Predicted Reactivity: Mouse, Rat, Xenopus)
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
UBE2Z; Polyclonal Antibody; UBE2Z Antibody (C-term); Ubiquitin-conjugating enzyme E2 Z; Uba6-specific E2 conjugating enzyme 1; Use1; Ubiquitin carrier protein Z; Ubiquitin-protein ligase Z; anti-UBE2Z antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse, Rat, Xenopus)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This UBE2Z antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-310 amino acids from the C-terminal region of human UBE2Z.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
284-310
Sequence Length
246
Applicable Applications for anti-UBE2Z antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(UBE2Z Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the UBE2Z antibody detected the UBE2Z protein (arrow).)
Western Blot (WB)
(UBE2Z Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the UBE2Z antibody detected the UBE2Z protein (arrow).)
Related Product Information for anti-UBE2Z antibody
Modification of proteins with ubiquitin (UBB; MIM 191339)
or ubiquitin-like proteins controls many signaling networks and
requires a ubiquitin activating enzyme (E1), a ubiquitin
conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE2Z
is an E2 enzyme (Jin et al., 2007 [PubMed 17597759]).[supplied by
OMIM].
or ubiquitin-like proteins controls many signaling networks and
requires a ubiquitin activating enzyme (E1), a ubiquitin
conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE2Z
is an E2 enzyme (Jin et al., 2007 [PubMed 17597759]).[supplied by
OMIM].
Product Categories/Family for anti-UBE2Z antibody
References
Gu, X., et al. Mol. Biol. Rep. 34(3):183-188(2007)
Jin, J., et al. Nature 447(7148):1135-1138(2007)
Jin, J., et al. Nature 447(7148):1135-1138(2007)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
38210
NCBI Official Full Name
ubiquitin-conjugating enzyme E2 Z
NCBI Official Synonym Full Names
ubiquitin-conjugating enzyme E2Z
NCBI Official Symbol
UBE2Z
NCBI Official Synonym Symbols
USE1; HOYS7
NCBI Protein Information
ubiquitin-conjugating enzyme E2 Z
UniProt Protein Name
Ubiquitin-conjugating enzyme E2 Z
Protein Family
UniProt Gene Name
UBE2Z
UniProt Synonym Gene Names
Use1
UniProt Entry Name
UBE2Z_HUMAN
NCBI Description
This gene encodes an enzyme which ubiquitinates proteins which participate in signaling pathways and apoptosis. [provided by RefSeq, Feb 2012]
Uniprot Description
UBE2Z: Catalyzes the covalent attachment of ubiquitin to other proteins. Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation. Belongs to the ubiquitin-conjugating enzyme family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Ligase; Ubiquitin ligase; Ubiquitin conjugating system; EC 6.3.2.19
Chromosomal Location of Human Ortholog: 17q21.32
Cellular Component: nucleoplasm; cytoplasm
Molecular Function: protein binding; small conjugating protein ligase activity; ubiquitin protein ligase binding; ATP binding; ligase activity
Biological Process: protein polyubiquitination; apoptosis
Research Articles on UBE2Z
Similar Products
Product Notes
The UBE2Z ube2z (Catalog #AAA9213125) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 284-310. The UBE2Z Antibody (C-term) reacts with Human (Predicted Reactivity: Mouse, Rat, Xenopus) and may cross-react with other species as described in the data sheet. AAA Biotech's UBE2Z can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the UBE2Z ube2z for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "UBE2Z, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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