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Rabbit TYW1B Polyclonal Antibody | anti-TYW1B antibody

TYW1B antibody

Gene Names
TYW1B; RSAFD2; LINC00069; NCRNA00069
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
TYW1B antibody was purified by Antigen Affinity chromatography
Synonyms
TYW1B; Polyclonal Antibody; TYW1B antibody; Polyclonal TYW1B; Anti-TYW1B; TRNA Yw Synthesizing Protein 1 Homolog B; Tyw1B; MGC87315; NcRNA00069; Rsafd2; anti-TYW1B antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
TYW1B antibody was purified by Antigen Affinity chromatography
Form/Format
Supplied in PBS buffer with 0.02% Sodium Azide and 50% Glycerol, pH 7.3
Sequence Length
189
Applicable Applications for anti-TYW1B antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Biological Significance
TYW1B is a probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.
Cross-Reactivity
Human, Mouse, Rat
Immunogen
TYW1B antibody was raised in Rabbit using Human TYW1B as the immunogen
Preparation and Storage
Store at 4 degree C for short term storage and -20 degree C for long term storage. Avoid repeat freeze/thaw cycles
Related Product Information for anti-TYW1B antibody
Rabbit polyclonal TYW1B antibody
Product Categories/Family for anti-TYW1B antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
34,060 Da
NCBI Official Full Name
TYW1B protein, partial
NCBI Official Synonym Full Names
tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)
NCBI Official Symbol
TYW1B
NCBI Official Synonym Symbols
RSAFD2; LINC00069; NCRNA00069
NCBI Protein Information
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase
UniProt Protein Name
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase
UniProt Gene Name
TYW1B
UniProt Synonym Gene Names
RSAFD2
UniProt Entry Name
TYW1B_HUMAN

NCBI Description

Wybutosine is a hypermodified guanosine found in phenylalanine tRNA. Wybutosine functions to stabilize codon-anticodon interactions during ribosome decoding and therefore supports the maintenance of the reading frame. In yeast, the homolog of this gene is essential for the synthesis of wybutosine. The human genome contains two closely related genes that putatively function in wybutosine synthesis. The open reading frame of this locus is disrupted in some individuals. Thus, this locus appears to be an evolving pseudogene, but may still be functional in some members of the population. [provided by RefSeq, Apr 2014]

Uniprot Description

TYW1B: Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Belongs to the TYW1 family.

Protein type: EC 4.1.3.44

Chromosomal Location of Human Ortholog: 7q11.23

Molecular Function: FMN binding; 4 iron, 4 sulfur cluster binding; iron ion binding; lyase activity; oxidoreductase activity

Biological Process: tRNA processing

Research Articles on TYW1B

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Product Notes

The TYW1B tyw1b (Catalog #AAA5302625) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TYW1B can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the TYW1B tyw1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TYW1B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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