Western Blot (WB)
(TXTP Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the TXTP antibody detected the TXTP protein (arrow).)
Rabbit anti-Human TXTP Polyclonal Antibody | anti-SLC25A1 antibody
TXTP Antibody (Center)
Western Blot (WB)
(TXTP Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the TXTP antibody detected the TXTP protein (arrow).)
Western Blot (WB)
(TXTP Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the TXTP antibody detected the TXTP protein (arrow).)
Immunohistochemistry (IHC)
(TXTP Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TXTP Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(TXTP Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TXTP Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(TXTP Antibody (Center) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(TXTP Antibody (Center) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Iacobazzi, V., et al. Biochem. Biophys. Res. Commun. 386(1):186-191(2009)
Trynka, G., et al. Gut 58(8):1078-1083(2009)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the mitochondrial carrier subfamily of solute carrier proteins. Members of this family include nuclear-encoded transporters that translocate small metabolites across the mitochondrial membrane. This protein regulates the movement of citrate across the inner membranes of the mitochondria. Mutations in this gene have been associated with combined D-2- and L-2-hydroxyglutaric aciduria. Pseudogenes of this gene have been identified on chromosomes 7, 11, 16, and 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Uniprot Description
SLC25A1: Involved in citrate-H(+)/malate exchange. Important for the bioenergetics of hepatic cells as it provides a carbon source for fatty acid and sterol biosyntheses, and NAD(+) for the glycolytic pathway. Belongs to the mitochondrial carrier family.
Protein type: Mitochondrial; Membrane protein, multi-pass; Transporter, SLC family; Transporter; Membrane protein, integral
Chromosomal Location of Human Ortholog: 22q11.21
Cellular Component: mitochondrial inner membrane; integral to membrane; nucleus
Molecular Function: citrate transmembrane transporter activity
Biological Process: citrate transport; carbohydrate metabolic process; glucose metabolic process; triacylglycerol biosynthetic process; pathogenesis; cellular lipid metabolic process; transmembrane transport; gluconeogenesis
Disease: Combined D-2- And L-2-hydroxyglutaric Aciduria
Research Articles on SLC25A1
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Product Notes
The SLC25A1 slc25a1 (Catalog #AAA9209706) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 142-170. The TXTP Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TXTP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the SLC25A1 slc25a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TXTP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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