Western Blot (WB)
(The anti-TrxL Pab is used in Western blot to detect TrxL in HL-60 cell lysate.)
Rabbit anti-Human TXNL1 Polyclonal Antibody | anti-TXNL1 antibody
TXNL1, CT (Thioredoxin-like Protein 1, 32kD Thioredoxin-related Protein, TXNL1, TRP32, TXL, TXNL, TrxL) (AP)
ELISA: 1:1,000
WB: 1:100-1:500
Applications are based on unconjugated antibody.
Western Blot (WB)
(The anti-TrxL Pab is used in Western blot to detect TrxL in HL-60 cell lysate.)
Western Blot (WB)
(The anti-TrxL Pab is used in Western blot to detect TrxL in HL-60 cell lysate.)
Testing Data
(Mouse cerebellar cortex showing molecular cell layer (mc), Purkinje cells (Pc) and granular cell layer. Trxl-1 gives strong nuclear labeling in Purkinje cells and granular cells with lower cytoplasmic staining. The results correspond precisely to TrxL-1 mRNA expression shown with in situ hybridization (Jiménez A et al. FEBS Lett. 2006, 580(3):960-7) and could be abolished with peptide used for immunization. The fixation was 4% paraformaldehyde perfusion (4mins) and 60 mins immersion. Staining was done in frozen sections with Vector Elite kit and nickel intensified DAB as a chromogen. Data courtesy of Prof. Markku Pelto-Huikko, Department of Developmental Biology, Medical School,Tampere University, Finland.)
Testing Data
(Mouse cerebellar cortex showing molecular cell layer (mc), Purkinje cells (Pc) and granular cell layer. Trxl-1 gives strong nuclear labeling in Purkinje cells and granular cells with lower cytoplasmic staining. The results correspond precisely to TrxL-1 mRNA expression shown with in situ hybridization (Jiménez A et al. FEBS Lett. 2006, 580(3):960-7) and could be abolished with peptide used for immunization. The fixation was 4% paraformaldehyde perfusion (4mins) and 60 mins immersion. Staining was done in frozen sections with Vector Elite kit and nickel intensified DAB as a chromogen. Data courtesy of Prof. Markku Pelto-Huikko, Department of Developmental Biology, Medical School,Tampere University, Finland.)
NCBI and Uniprot Product Information
Uniprot Description
TXNL1: a thiol reductase and novel subunit of the proteasome 19S particle. Interconverts reduced sulfide groups and oxidized disulfide bonds in a substrate.
Protein type: Oxidoreductase
Chromosomal Location of Human Ortholog: 18q21.31
Cellular Component: proteasome complex; cytoplasm; nucleus
Molecular Function: disulfide oxidoreductase activity; protein disulfide oxidoreductase activity
Biological Process: cell redox homeostasis; glycerol ether metabolic process
Research Articles on TXNL1
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Product Notes
The TXNL1 txnl1 (Catalog #AAA6502481) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TXNL1, CT (Thioredoxin-like Protein 1, 32kD Thioredoxin-related Protein, TXNL1, TRP32, TXL, TXNL, TrxL) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TXNL1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB). IHC: 1:50-1:100 ELISA: 1:1,000 WB: 1:100-1:500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the TXNL1 txnl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TXNL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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